Dysregulation of galectin expression is frequently observed in cancer tissues. Such an
abnormal expression pattern often correlates with aggressiveness and relapse in many types of …

The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …

Matrix metalloproteinase 9 (MMP-9) is one of the most studied enzymes in cancer. MMP-9
can cleave proteins of the extracellular matrix and a large number of receptors and growth …

Background In 2014, breast cancer remains a major cause of mortality worldwide mostly
due to tumor relapse and metastasis. There is currently a great interest in identifying cancer …

Purpose: Although the murine orthologue of glycoprotein nonmetastatic B (GPNMB),
Osteoactivin, promotes breast cancer metastasis in an in vivo mouse model, its importance in …

Human leukocyte elastase (HLE) participates in tissue destruction in a number of inflammatory
disorders, including rheumatoid arthritis and cystic fibrosis. Since HLE has been shown to …

The regulation of matrix metalloproteinase-9 (MMP-9) expression in glioma cells is one of
the key processes in tumor invasion through the brain extracellular matrix. Although some …

OBJECTIVE: To investigate whether 14-3-3 proteins were detectable in synovial fluid (SF) of
patients with inflamed joints, and if so, what isoform(s); and to examine whether there was a …

Acidic extracellular pH is a common feature of tumor tissues. We have reported that culturing
cells at acidic pH (5.4–6.5) induced matrix metalloproteinase‐9 expression through …

Metastasis is a multistep process by which cancer cells, after acquiring several capabilities,
spread to distinct sites in the body. It is the major cause of death in individuals suffering from …