Objective To evaluate the efficacy and safety of tocilizumab, an interleukin-6 receptor
antibody, in patients with adult-onset Still’s disease. Methods In this double-blind, randomised, …

Background The aim of this study was to elucidate the function of circulating follicular helper
T (Tfh) cell subsets in helping B cells in patients with active, untreated IgG4-related disease (…

Objective To elucidate the pathologic role of follicular helper T (Tfh) cells and their subsets
in active, untreated IgG4‐related disease. Methods Fifteen patients with active, untreated, …

Objective To identify initial predictors of poor survival in patients with PM/DM-associated
interstitial lung disease (ILD). Methods We established a multicentre retrospective cohort of …

IgG4-related disease (IgG4-RD) is a recently recognized disease entity characterized by high
serum IgG4 concentrations and infiltration of IgG4 + plasma cells with hyperplastic ectopic …

The objective of the study was to identify risk factors for acute exacerbation of interstitial lung
disease (ILD) during tocilizumab treatment in patients with rheumatoid arthritis (RA). This is …

Objective To evaluate the sustained remission and low disease activity after discontinuation
of tocilizumab in patients with rheumatoid arthritis who were treated with tocilizumab alone …

Rheumatoid arthritis is an autoimmune disease that primarily affects the joints. The
emergence of highly effective anti-rheumatic drugs such as biologic agents and janus kinase …

Importance The current standard induction therapy for antineutrophil cytoplasm antibody (ANCA)–associated
vasculitis is the combination of high-dose glucocorticoids and …

Objective To establish predictive models for mortality in patients with polymyositis/dermatomyositis–associated
interstitial lung disease (PM/DM‐ILD) using a combination of initial serum …