Background An increasing number of NFKB1 variants are being identified in patients with
heterogeneous immunologic phenotypes. Objective To characterize the clinical and cellular …

… Alba P, Karim MY, Hunt BJ. Mycophenolate mofetil as a treatment for autoimmune haemolytic
anaemia in patients with systemic lupus erythematosus and antiphospholipid syndrome. …

PURPOSE: Thalidomide is effective for the treatment of severe cutaneous lupus. Our aim
was to study the safety and efficacy of different doses of thalidomide in this condition. …

Atherosclerosis is now recognized as a chronic inflammatory disease and is characterized
by features of inflammation at all stages of its development. It also appears to display …

Methods Some studies have shown the efficacy of intravenous immunoglobulin (IVIG) in the
treatment of systemic lupus erythematosus (SLE) but its use still lacks confirmation in large …

Common variable immunodeficiency (CVID) represents a heterogeneous group of rare
disorders. There is considerable morbidity and mortality as a result of non-infectious …

Aims The effects of mannose-binding lectin (MBL) deficiency are well known in children and
in those with a compromised immune system. However, its effects in adults are debateable, …

Cytokines play an important role in the pathogenesis of systemic lupus erythematosus (SLE)
and lupus nephritis. This is currently a very active area of research. Of particular interest is …

Objectives The association of B cell targeted therapies with development of
hypogammaglobulinaemia and infection is increasingly recognized. Our aim was to develop …

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterised by
abnormal autoantibody production and clearance. This immunological background has been …