In Japan, original researches on nephrotic syndrome (NS) were initially performed by the
Ministry of Health, Labour and Welfare (MHLW) NS research group. The first definition of NS …

Proteinuria has been considered to be the hallmark of diabetic kidney disease and to precede
renal function loss. However, it has become clear that a substantial proportion of patients …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney
disease, with approximately half of the patients experiencing end-stage renal disease by …

Results The median follow-up period was 2.3 years (interquartile range, 1.1–5.3), and the
primary outcome was noted in 94 patients. Mean eGFR was 46.3±23.2 ml/min per 1.73 m 2, …

OBJECTIVE Clinicopathological characteristics, renal prognosis, and mortality in patients
with type 2 diabetes and reduced renal function without overt proteinuria are scarce. …

Introduction Immunoglobulin G4 (IgG4)–related aortitis/periaortitis and periarteritis are vascular
manifestations of IgG4-related disease. In this disease, the affected aneurysmal lesion …

Background A new classification of diabetic nephropathy was reported by Tervaert et al., but
the association between pathological findings and the clinical outcomes remains unclear. …

Methods We measured levels of anti-carbonic anhydrase II antibody in serum samples from
46 patients who had been diagnosed with primary Sjögren syndrome and who were …

Background The aim of this study was to evaluate the clinical manifestations and prevalence
of familial Mediterranean fever (FMF) in Japanese patients with unexplained fever and …

Background The clinical and pathologic manifestations of nephropathy due to type 2 diabetes
are diverse, but large-scale pathologic studies with long-term observations are limited. …