Bone resorption inhibitors from hop extract
H Tobe, Y Muraki, K Kitamura… - Bioscience …, 1997 - Taylor & Francis
We searched hop extract for active component(s) that inhibited bone resorption in the pit
formation assay, and isolated xanthohumol and humulone as active ingredients. Especially …
formation assay, and isolated xanthohumol and humulone as active ingredients. Especially …
Structural and functional properties of hen egg-white lysozyme deamidated by protein engineering
A Kato, S Tanimoto, Y Muraki, K Kobayashi… - Bioscience …, 1992 - jstage.jst.go.jp
Materials and Methods Materials. T4DNA ligase, alkaline phosphatase and restriction enzymes
were purchased from Takara Shuzo Co.(Kyoto). The Takara 7-DEAZA sequence kit for …
were purchased from Takara Shuzo Co.(Kyoto). The Takara 7-DEAZA sequence kit for …
Polymorphisms of IL-1 beta gene in Japanese patients with Sjögren's syndrome and systemic lupus erythematosus.
Y Muraki, A Tsutsumi, R Takahashi, E Suzuki… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: Interleukin (IL)-1 beta is a proinflammatory cytokine involved in various
immune responses. Five polymorphisms in the IL-1 beta gene have been described, and …
immune responses. Five polymorphisms in the IL-1 beta gene have been described, and …
Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals
…, H Suzuki, E Suzuki, M Sugihara, Y Muraki… - Modern …, 2008 - academic.oup.com
Tristetraprolin (TTP) is an intracellular protein that modulates the production of cytokines,
including TNFα, by binding to and destabilizing the mRNAs of these cytokines. Therefore, …
including TNFα, by binding to and destabilizing the mRNAs of these cytokines. Therefore, …
Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production
Y Muraki, I Matsumoto, Y Chino, T Hayashi… - Biochemical and …, 2004 - Elsevier
Glucose-6-phosphate isomerase (GPI), recognized as an autoantigen in the K/BxN arthritis
model, is a ubiquitous cytoplasmic enzyme. Anti-GPI antibodies (Abs) are also detected in …
model, is a ubiquitous cytoplasmic enzyme. Anti-GPI antibodies (Abs) are also detected in …
Monomeric and dimeric GDF-5 show equal type I receptor binding and oligomerization capability and have the same biological activity
…, R Bechtold, M Hanke, S Kawai, Y Muraki… - 2006 - degruyter.com
Growth and differentiation factor 5 (GDF-5) is a homodimeric protein stabilized by a single
disulfide bridge between cysteine 465 in the respective monomers, as well as by three …
disulfide bridge between cysteine 465 in the respective monomers, as well as by three …
Relationships between conformational stabilities and surface functional properties of mutant hen egg-white lysozymes constructed by genetic engineering
A Kato, S Tanimoto, Y Muraki, Y Oda… - Journal of Agricultural …, 1994 - ACS Publications
MATERIALS AND METHODS Materials. T4DNA ligase, alkaline phosphatase and restric-tion
enzymes were purchased from Takara Shuzo Co.(Kyoto). The Takara 7-DEAZA sequence …
enzymes were purchased from Takara Shuzo Co.(Kyoto). The Takara 7-DEAZA sequence …
[HTML][HTML] A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase …
I Matsumoto, H Zhang, Y Muraki, T Hayashi… - Arthritis research & …, 2005 - Springer
Anti-glucose-6-phosphate isomerase (GPI) antibodies are known to be arthritogenic autoantibodies
in K/B×N mice, although some groups have reported that few healthy humans retain …
in K/B×N mice, although some groups have reported that few healthy humans retain …
The exploration of joint-specific immunoreactions on immunoglobulins G of anti-glucose-6-phosphate isomerase antibody-positive patients with rheumatoid arthritis
I Matsumoto, Y Muraki… - International …, 2005 - spandidos-publications.com
The pathogenic role of autoantibodies in rheumatoid arthritis (RA) remains elusive. Anti-glucose-6-phosphate
isomerase (GPI) antibodies (Abs) are candidates for arthritogenic Abs …
isomerase (GPI) antibodies (Abs) are candidates for arthritogenic Abs …
Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis
T Hayashi, I Matsumoto, Y Muraki… - Modern …, 2005 - Taylor & Francis
Anti-glucose-6-phosphate isomerase (GPI) antibodies (Abs) are known to be arthritogenic
in mice. These Abs are elevated in several forms of arthritic condition in humans, although …
in mice. These Abs are elevated in several forms of arthritic condition in humans, although …