Human parvovirus B19 as a causative agent for rheumatoid arthritis
…, C Murai, S Shibata, Y Munakata… - Proceedings of the …, 1998 - National Acad Sciences
Human parvovirus B19 (B19) DNA was detected in the synovial tissues in 30 of 39 patients
with rheumatoid arthritis (RA), and infrequently in those with osteoarthritis and traumatic joints…
with rheumatoid arthritis (RA), and infrequently in those with osteoarthritis and traumatic joints…
Ku80 autoantigen as a cellular coreceptor for human parvovirus B19 infection
Y Munakata, T Saito-Ito, K Kumura-Ishii, J Huang… - Blood, 2005 - ashpublications.org
Human parvovirus B19 (B19) infects human erythroid cells expressing P antigen. However,
some cell lines that were positive for P antigen failed to bind B19, whereas some cell lines …
some cell lines that were positive for P antigen failed to bind B19, whereas some cell lines …
Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation
H Ikushima, Y Munakata, T Ishii… - Proceedings of the …, 2000 - National Acad Sciences
CD26 is a T cell activation antigen known to bind adenosine deaminase and have dipeptidyl
peptidase IV activity. Cross-linking of CD26 and CD3 with immobilized mAbs can deliver a …
peptidase IV activity. Cross-linking of CD26 and CD3 with immobilized mAbs can deliver a …
Regulation of tumor necrosis factor alpha promoter by human parvovirus B19 NS1 through activation of AP-1 and AP-2
Y Fu, KK Ishii, Y Munakata, T Saitoh, M Kaku… - Journal of …, 2002 - Am Soc Microbiol
Human parvovirus B19 frequently causes acute and chronic arthritis in adults. The molecular
mechanism of B19 arthritis, however, remains poorly understood. We previously showed …
mechanism of B19 arthritis, however, remains poorly understood. We previously showed …
Tofacitinib in combination with methotrexate in patients with rheumatoid arthritis: clinical efficacy, radiographic, and safety outcomes from a twenty‐four–month, phase …
…, N Miyasaka, S Mori, Y Munakata… - Arthritis & …, 2019 - Wiley Online Library
Objective Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis ( RA ).
The phase III , 24‐month, placebo‐controlled Oral Rheumatoid Arthritis ( ORAL ) Scan trial …
The phase III , 24‐month, placebo‐controlled Oral Rheumatoid Arthritis ( ORAL ) Scan trial …
Determination of adenosine deaminase binding domain on CD26 and its immunoregulatory effect on T cell activation.
…, K Tachibana, M Hegen, Y Munakata… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
CD26, a 110-kDa cell surface glycoprotein, exhibits dipeptidyl peptidase IV enzyme activity
and plays an important role in T cell costimulation. In the present study, we examined both …
and plays an important role in T cell costimulation. In the present study, we examined both …
CD26/dipeptidyl peptidase IV differentially regulates the chemotaxis of T cells and monocytes toward RANTES: possible mechanism for the switch from innate to …
S Iwata, N Yamaguchi, Y Munakata… - International …, 1999 - academic.oup.com
CD26, a 110 kDa cell surface glycoprotein, exhibits dipeptidyl peptidase IV (DPPIV; EC 3.4.14.5)
enzyme activity and plays an important role in T cell co-stimulation. In the present study, …
enzyme activity and plays an important role in T cell co-stimulation. In the present study, …
Soluble CD26/dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/insulin-like growth factor II receptor
H Ikushima, Y Munakata, S Iwata, K Ohnuma… - Cellular …, 2002 - Elsevier
CD26 is a T cell surface molecule with dipeptidyl peptidase IV (DPPIV) enzyme activity in its
extracellular region. In addition to its membrane form, CD26 exists in plasma as a soluble …
extracellular region. In addition to its membrane form, CD26 exists in plasma as a soluble …
Intrathyroidal persistence of human parvovirus B19 DNA in a patient with Hashimoto's thyroiditis
K Mori, Y Munakata, T Saito, J Tani, Y Nakagawa… - Journal of Infection, 2007 - Elsevier
Previous studies suggest a role of viral infection in the development of Hashimoto's thyroiditis
(HT). Here we report a patient with HT in whom human parvovirus B19 (B19) DNA has …
(HT). Here we report a patient with HT in whom human parvovirus B19 (B19) DNA has …
Longterm safety and efficacy of subcutaneous tocilizumab monotherapy: results from the 2-year open-label extension of the MUSASHI study
…, H Miyahara, T Miyamoto, Y Munakata… - The Journal of …, 2015 - jrheum.org
Objective. To evaluate the longterm safety and efficacy of subcutaneous tocilizumab (TCZ-SC)
as monotherapy in patients with rheumatoid arthritis (RA). Methods. Of 346 patients who …
as monotherapy in patients with rheumatoid arthritis (RA). Methods. Of 346 patients who …