User profiles for Yanli Wang

Yanli Wang, MD, PhD

The Children's Hospital of Philadelphia
Verified email at chop.edu
Cited by 4185

Database resources of the national center for biotechnology information

…, TA Tatusova, L Wagner, Y Wang… - Nucleic acids …, 2010 - academic.oup.com
In addition to maintaining the GenBank® nucleic acid sequence database, the National
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the …

First principles study of structural, vibrational and electronic properties of graphene-like MX2 (M= Mo, Nb, W, Ta; X= S, Se, Te) monolayers

Y Ding, Y Wang, J Ni, L Shi, S Shi, W Tang - Physica B: Condensed Matter, 2011 - Elsevier
Using first principles calculations, we investigate the structural, vibrational and electronic
structures of the monolayer graphene-like transition-metal dichalcogenide (MX 2 ) sheets. We …

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

Y Wang, S Juranek, H Li, G Sheng, T Tuschl, DJ Patel - nature, 2008 - nature.com
Here we report on a 3.0 Å crystal structure of a ternary complex of wild-type Thermus
thermophilus argonaute bound to a 5′-phosphorylated 21-nucleotide guide DNA and a 20-…

[HTML][HTML] A comparative encyclopedia of DNA elements in the mouse genome

…, A Skoultchi, S Gosh, C Disteche, P Treuting, Y Wang… - Nature, 2014 - nature.com
The laboratory mouse shares the majority of its protein-coding genes with humans, making
it the premier model organism in biomedical research, yet the two mammals differ in …

[HTML][HTML] Topologically associating domains are stable units of replication-timing regulation

…, V Dileep, F Yue, W Wu, O Denas, DL Vera, Y Wang… - Nature, 2014 - nature.com
Eukaryotic chromosomes replicate in a temporal order known as the replication-timing
program 1 . In mammals, replication timing is cell-type-specific with at least half the genome …

Structure of the guide-strand-containing argonaute silencing complex

Y Wang, G Sheng, S Juranek, T Tuschl, DJ Patel - Nature, 2008 - nature.com
The slicer activity of the RNA-induced silencing complex is associated with argonaute, the
RNase H-like PIWI domain of which catalyses guide-strand-mediated sequence-specific …

PubChem: integrated platform of small molecules and biological activities

EE Bolton, Y Wang, PA Thiessen, SH Bryant - Annual reports in …, 2008 - Elsevier
PubChem is an open repository for experimental data identifying the biological activities of
small molecules. PubChem contents include more than: 1000 bioassays, 28 million bioassay …

PubChem: a public information system for analyzing bioactivities of small molecules

Y Wang, J Xiao, TO Suzek, J Zhang… - Nucleic acids …, 2009 - academic.oup.com
PubChem ( http://pubchem.ncbi.nlm.nih.gov ) is a public repository for biological properties
of small molecules hosted by the US National Institutes of Health (NIH). PubChem BioAssay …

[HTML][HTML] Gram-scale synthesis of single-crystalline graphene quantum dots with superior optical properties

L Wang, Y Wang, T Xu, H Liao, C Yao, Y Liu… - Nature …, 2014 - nature.com
Graphene quantum dots (GQDs) have various alluring properties and potential applications,
but their large-scale applications are limited by current synthetic methods that commonly …

CDD: a curated Entrez database of conserved domain alignments

…, PA Thiessen, S Vasudevan, Y Wang… - Nucleic acids …, 2003 - academic.oup.com
The Conserved Domain Database (CDD) is now indexed as a separate database within the
Entrez system and linked to other Entrez databases such as MEDLINE®. This allows users …