[HTML][HTML] Interleukin-18 in inflammatory kidney disease

Y Hirooka, Y Nozaki - Frontiers in medicine, 2021 - frontiersin.org
Interleukin (IL)-18, a member of the IL-1 superfamily, is a pro-inflammatory cytokine that is
structurally similar to IL-1β. IL-18 promotes the production of interferon gamma (IFN-γ) and …

Anti-inflammatory effect of all-trans-retinoic acid in inflammatory arthritis

Y Nozaki, T Yamagata, M Sugiyama, S Ikoma… - Clinical …, 2006 - Elsevier
OBJECTIVE:: To determine whether all-trans-retinoic acid (ATRA) improves the destruction
of joints and the effect of cytokines on DBA/1J mice with collagen-induced arthritis (CIA). …

Temperature and parasitic photocurrent effects in dynamic vision sensors

Y Nozaki, T Delbruck - IEEE Transactions on Electron Devices, 2017 - ieeexplore.ieee.org
The effect of temperature and parasitic photocurrent on event-based dynamic vision sensors
(DVS) is important because of their application in uncontrolled robotic, automotive, and …

[HTML][HTML] Protective effect and mechanism of IL-10 on renal ischemia–reperfusion injury

K Sakai, Y Nozaki, Y Murao, T Yano, J Ri, K Niki… - Laboratory …, 2019 - Elsevier
Interleukin (IL)-10, a cytokine with anti-inflammatory effects, is produced by blood cells and
cells of various organs. Ischemia–reperfusion injury (IRI) is a systemic inflammatory disease …

Retinoic acid reduces autoimmune renal injury and increases survival in NZB/W F1 mice

K Kinoshita, BS Yoo, Y Nozaki, M Sugiyama… - The Journal of …, 2003 - journals.aai.org
Retinoic acids, a group of natural and synthetic vitamin A derivatives, have potent antiproliferative
and anti-inflammatory properties. Recently, retinoic acids were reported to inhibit Th1 …

[HTML][HTML] Signaling through the interleukin-18 receptor α attenuates inflammation in cisplatin-induced acute kidney injury

Y Nozaki, K Kinoshita, T Yano, K Asato, T Shiga… - Kidney international, 2012 - Elsevier
Interleukin (IL)-18 is produced by leukocytes and renal parenchymal cells (tubular epithelial
cells, podocytes, and mesangial cells). The IL-18 receptor (IL-18R) is expressed on these …

[HTML][HTML] Usefulness of interleukin-18 as a diagnostic biomarker to differentiate adult-onset Still's disease with/without macrophage activation syndrome from other …

T Shiga, Y Nozaki, D Tomita, K Kishimoto… - Frontiers in …, 2021 - frontiersin.org
Background Interleukin (IL)-18 is markedly elevated in systemic inflammatory diseases that
cause the ‘cytokine storm’ such as adult-onset Still’s disease (AOSD) and hemophagocytic …

Mast cells mediate acute kidney injury through the production of TNF

…, J Chan, PY Gan, L Dewage, Y Nozaki… - Journal of the …, 2011 - journals.lww.com
Leukocyte recruitment contributes to acute kidney injury (AKI), but the mechanisms by which
leukocytes promote injury are not completely understood. The degranulation of mast cells …

[HTML][HTML] Predictive modeling for odor character of a chemical using machine learning combined with natural language processing

Y Nozaki, T Nakamoto - PloS one, 2018 - journals.plos.org
Recent studies on machine learning technology have reported successful performances in
some visual and auditory recognition tasks, while little has been reported in the field of …

Blockade of IL-18 receptor signaling delays the onset of autoimmune disease in MRL-Faslpr mice

K Kinoshita, T Yamagata, Y Nozaki… - The journal of …, 2004 - journals.aai.org
Autoimmune disease in Fas-deficient MRL-Fas lpr mice is dependent on infiltrating autoreactive
leukocytes and autoantibodies, and IFN-γ plays an important role in the pathogenesis. …