Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton
…, GP Taylor, JN Weber, GM Griffiths, Y Tanaka… - Science, 2003 - science.org
Cell contact is required for efficient transmission of human T cell leukemia virus– type 1 (HTLV-I)
between cells and between individuals, because naturally infected lymphocytes …
between cells and between individuals, because naturally infected lymphocytes …
Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse Th cell-polarizing signals
…, P Kalinski, JHN Schuitemaker, Y Tanaka… - The Journal of …, 2002 - journals.aai.org
Upon microbial infection, specific Th1 or Th2 responses develop depending on the type of
microbe. Here, we demonstrate that different microbial compounds polarize the maturation of …
microbe. Here, we demonstrate that different microbial compounds polarize the maturation of …
Expression and function of OX40 ligand on human dendritic cells.
Y Ohshima, Y Tanaka, H Tozawa… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
OX40 ligand (OX40L), a member of the TNF family, was shown to be capable of signaling
both the cells on which it is expressed and those expressing OX40, its cognate receptor. Here …
both the cells on which it is expressed and those expressing OX40, its cognate receptor. Here …
Genetic and epigenetic inactivation of tax gene in adult T‐cell leukemia cells
…, J Yasunaga, K Nosaka, Y Tanaka… - … journal of cancer, 2004 - Wiley Online Library
To clarify the status of tax gene, we analyzed human T‐cell leukemia virus type‐I (HTLV‐I)
associated cell lines and fresh adult T‐cell leukemia (ATL) cells. We compared 2 types of …
associated cell lines and fresh adult T‐cell leukemia (ATL) cells. We compared 2 types of …
The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells.
…, T Hori, K Imada, T Ishikawa, Y Tanaka… - The Journal of …, 1996 - rupress.org
Fresh leukemic cells from patients with adult T cell leukemia (ATL) and some ATL-derived T
cell lines show adhesion to human umbilical vein endothelial cells (HUVECs) mainly …
cell lines show adhesion to human umbilical vein endothelial cells (HUVECs) mainly …
Bay 11-7082 inhibits transcription factor NF-κB and induces apoptosis of HTLV-I–infected T-cell lines and primary adult T-cell leukemia cells
…, Y Yamasaki, K Tsukasaki, Y Tanaka… - Blood, The Journal …, 2002 - ashpublications.org
Human T-cell leukemia virus type I (HTLV-I) is the causative agent of an aggressive form of
leukemia designated adult T-cell leukemia (ATL). We have previously demonstrated that all T-…
leukemia designated adult T-cell leukemia (ATL). We have previously demonstrated that all T-…
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions
It is important to understand which molecules are relevant for linking innate and adaptive
immune cells. In this study, we show that OX40 ligand is selectively induced on IL-2, IL-12, or IL-…
immune cells. In this study, we show that OX40 ligand is selectively induced on IL-2, IL-12, or IL-…
OX40 Costimulation Enhances Interleukin-4 (IL-4) Expression at Priming and Promotes the Differentiation of Naive Human CD4+ T Cells Into High IL-4–Producing …
…, LP Yang, T Uchiyama, Y Tanaka… - Blood, The Journal …, 1998 - ashpublications.org
Th2 cell development is critically dependent on the presence of interleukin-4 (IL-4) at priming.
The cellular origin and the mechanisms regulating this early production of IL-4 at the site …
The cellular origin and the mechanisms regulating this early production of IL-4 at the site …
Abundant tax protein expression in CD4+ T cells infected with human T-cell lymphotropic virus type I (HTLV-I) is prevented by cytotoxic T lymphocytes
…, GP Taylor, M Saito, R Davis, Y Tanaka… - Blood, The Journal …, 2000 - ashpublications.org
The role of the cellular immune response in human T-cell leukemia virus type I (HTLV-I)
infection is not fully understood. A persistently activated cytotoxic T lymphocyte (CTL) response …
infection is not fully understood. A persistently activated cytotoxic T lymphocyte (CTL) response …
Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation
…, EC Burton, D Savino, T Hori, Y Tanaka… - Journal of Experimental …, 2011 - rupress.org
The human breast tumor microenvironment can display features of T helper type 2 (Th2)
inflammation, and Th2 inflammation can promote tumor development. However, the molecular …
inflammation, and Th2 inflammation can promote tumor development. However, the molecular …