Methotrexate/iatrogenic lymphoproliferative disorders in rheumatoid arthritis: Histology, E pstein–B arr virus, and clonality are important predictors of disease …

…, K Sato, H Miyoshi, D Niino, Y Kimura… - European journal of …, 2013 - Wiley Online Library
Objectives Patients with rheumatoid arthritis ( RA ) may develop lymphoproliferative
disorders ( RA ‐ LPD ). Immunosuppressive states due to methotrexate ( MTX ) and Epstein–Barr …

Distribution of malignant lymphoma in Japan: analysis of 2260 cases, 2001–2006

…, Y Sugita, Y Nomura, K Shimizu, Y Kimura… - Pathology …, 2008 - Wiley Online Library
The World Health Organization classification was used to conduct an analysis of geographic,
age, sex, and lesion primarily biopsied/resected distribution of 2260 lymphoid neoplasms …

Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T‐cell lymphoma (AITL)

…, T Murayama, R Aoki, Y Kimura… - Pathology …, 2010 - Wiley Online Library
Angioimmunoblastic T‐cell lymphoma (AITL) is a peripheral T‐cell lymphoma characterized
by systemic disease with polymorphous infiltrate including macrophages. Although many …

Clinicopathological analysis of a composite lymphoma containing both T‐and B‐cell lymphomas

…, D Niino, F Arakawa, K Karube, Y Kimura… - Pathology …, 2012 - Wiley Online Library
Composite lymphomas (CLs) have been reported in 1–4.7% of all lymphomas, however, CLs
containing both T‐ and B‐cell lymphomas (CTBLs) are very rare. Here, we examined the …

[HTML][HTML] The relationship of FOXP3 expression and clinicopathological characteristics in adult T-cell leukemia/lymphoma

…, Y Sugita, S Yoshida, Y Nomura, K Shimizu, Y Kimura… - Modern Pathology, 2008 - Elsevier
Adult T-cell leukemia/lymphoma is an aggressive malignant disease associated with regulatory
T cells as discussed in some recent reports. We analyzed the expression of FOXP3, a …

Clinicopathologic analysis of peripheral T-cell lymphoma, follicular variant, and comparison with angioimmunoblastic T-cell lymphoma: Bcl-6 expression might affect …

…, K Sato, D Niino, F Arakawa, Y Kimura… - American journal of …, 2012 - academic.oup.com
We examined clinicopathologic findings in 17 cases of peripheral T-cell lymphoma, follicular
variant (f-PTCL), and compared these findings with angioimmunoblastic T-cell lymphoma (…

Malignant lymphoma of the spleen in Japan: a clinicopathological analysis of 115 cases

K Shimizu‐Kohno, Y Kimura, J Kiyasu… - Pathology …, 2012 - Wiley Online Library
Primary splenic lymphoma is rare, but malignant lymphoma often produces a lesion in the
spleen as part of systemic disease. The frequency of splenic malignant lymphoma in Japan is …

[HTML][HTML] BCL6 gene amplification/3q27 gain is associated with unique clinicopathological characteristics among follicular lymphoma without BCL2 gene translocation

…, G Ying, H Tagawa, D Niino, R Aoki, Y Kimura… - Modern …, 2008 - nature.com
Although approximately 10–20% cases of follicular lymphoma lack BCL2 gene rearrangement,
there are few reports having described the alternative genetic aberrations and their …

Clinicopathological features and prognostic significance of CXCL12 in blastic plasmacytoid dendritic cell neoplasm

…, T Nakama, J Kiyasu, K Sato, Y Kimura… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Blastic plasmacytoid dendritic cell neoplasm (BPDC) is a rare hematologic
neoplasm, which almost always involves the skin and shows poor prognosis. OBJECTIVE: …

Small cell variant of mantle cell lymphoma is an indolent lymphoma characterized by bone marrow involvement, splenomegaly, and a low Ki‐67 index

Y Kimura, K Sato, Y Imamura, F Arakawa… - Cancer …, 2011 - Wiley Online Library
Mantle cell lymphoma (MCL) is recognized as a well‐defined B cell neoplasm characterized
by overexpression of cyclin D1 (CCND1), with “classical” and “aggressive” variant subtypes. …