Aim To evaluate the correlation between circulating cell‐free DNA (ccfDNA) in plasma and
clinical disease activities in patients with rheumatoid arthritis (RA). Method The study group …

Since the emergence of COVID-19, several SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) variants have emerged and spread widely. These variants are produced …

For binary aqueous solvent mixtures the solvent composition in the first solvation sphere of
Eu3+ has been determined at 25 C by measuring the luminescence lifetime. In the systems …

Tumor necrosis factor (TNF)-α is responsible for expressions of several clock genes and affects
joint symptoms of rheumatoid arthritis (RA) with diurnal fluctuation. We tried to determine …

An attempt has been made to illustrate features of the growth cone of living nerve fibers
precisely and especially the behavior of filopodia toward various kinds of obstructions in tissue …

Objective: To elucidate the roles of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α)
in cell cycle regulation and proliferation of rheumatoid arthritis fibroblast-like synovial cells (…

Objectives: Rheumatoid Arthritis (RA) is the autoimmune disease representing the circadian
variations of symptoms such as morning stiffness of joints or increased production of …

Background Effects of methotrexate (MTX) on the proliferation of rheumatoid arthritis (RA)
synovial fibroblasts are incompletely understood. We explored actions of MTX in view of …

Replication-competent retrovirus (RCR) vectors have been shown to achieve significantly
enhanced tumor transduction efficiency and therapeutic efficacy in various cancer models. In …

Background Malignant mesothelioma is a highly aggressive tumor with poor prognosis. We
hypothesized that the tumor‐specific midkine (Mdk) promoter could confer transcriptional …