IL-25 enhances allergic airway inflammation by amplifying a TH2 cell–dependent pathway in mice

…, K Ikeda, S Kagami, M Hatano, Y Seto… - Journal of allergy and …, 2006 - Elsevier
BACKGROUND: A novel IL-17 family cytokine, IL-25, has been reported to induce IL-4, IL-5,
and IL-13 production from undefined non-T/non-B cells and then induce T H 2-type immune …

Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line Cε transcription of IL-4–stimulated B cells

…, K Hirose, K Suzuki, S Kagami, Y Seto… - Blood, The Journal …, 2002 - ashpublications.org
Interleukin 21 (IL-21) has recently been identified as a multifunctional cytokine that induces
the proliferation of T cells and B cells and differentiation of natural killer cells. To determine …

Drug treatment algorithm and recommendations from the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of …

…, M Kohno, S Hirata, M Kishimoto, Y Seto… - Modern …, 2023 - academic.oup.com
Objective The aim of this study was to update the Japan College of Rheumatology (JCR)
clinical practice guidelines (CPG) for the management of rheumatoid arthritis (RA; JCR CPG for …

C‐reactive protein as a predictor of infliximab treatment outcome in patients with rheumatoid arthritis: defining subtypes of nonresponse and subsequent response to …

MH Buch, Y Seto, SJ Bingham… - … : Official Journal of …, 2005 - Wiley Online Library
Objective Nonresponse to anti–tumor necrosis factor α in patients with rheumatoid arthritis (RA)
is poorly understood. The aims of this study were to define nonresponse patterns using …

Management of rheumatoid arthritis: the 2012 perspective

H Yamanaka, Y Seto, E Tanaka, T Furuya… - Modern …, 2013 - Taylor & Francis
Management of rheumatoid arthritis (RA) has improved over the last 10 years. These
changes have been monitored in the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) …

Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice

Y Seto, H Nakajima, A Suto, K Shimoda… - The Journal of …, 2003 - journals.aai.org
Allergic inflammation is mediated by Th2 cell-derived cytokines, including IL-4, IL-5, and IL-13,
and down-regulated by IFN-γ and IL-12. Tyk2 is a member of the Janus family of protein …

Presence of comorbidity affects both treatment strategies and outcomes in disease activity, physical function, and quality of life in patients with rheumatoid arthritis

…, A Kobayashi, K Shidara, N Sugimoto, Y Seto… - Clinical …, 2015 - Springer
To clarify the impact of comorbidities on treatment strategies and outcomes in patients with
rheumatoid arthritis (RA) using a large observational RA cohort, the presence of …

Postoperative complications in patients with rheumatoid arthritis using a biological agent–a systematic review and meta-analysis

…, Y Kawahito, M Kishimoto, Y Seto… - Modern …, 2015 - academic.oup.com
Objectives. To evaluate, through a systematic review of the literature, the association between
the use of biological disease-modifying antirheumatic drugs (bDMARDs) and surgical site …

Systematic review and meta-analysis of biosimilar for the treatment of rheumatoid arthritis informing the 2020 update of the Japan College of Rheumatology clinical …

…, M Kishimoto, Y Kaneko, H Tamai, Y Seto… - Modern …, 2022 - academic.oup.com
Objectives To evaluate the efficacy and safety of biosimilars compared with reference biological
disease modifying antirheumatic drugs (bDMARDs) in patients with rheumatoid arthritis (…

Does exercise therapy improve patient-reported outcomes in rheumatoid arthritis? A systematic review and meta-analysis for the update of the 2020 JCR guidelines …

…, M Kishimoto, M Kohno, T Sugihara, Y Seto… - Modern …, 2022 - academic.oup.com
Objectives This study aimed to evaluate the impact of exercise therapy on patient-reported
outcomes (PROs) in rheumatoid arthritis (RA) as part of the process of updating the 2020 …