The belle detector

…, Y Higashi, N Hitomi, S Igarashi, Y Igarashi… - Nuclear Instruments and …, 2002 - Elsevier
… In these synchrotron radiation calculations, we protect against beam tails out to 10σ x and
30σ y . The beam–beam simulations indicate no long tails in the interaction region. Mask-A …

Endothelial function and oxidative stress in cardiovascular diseases

Y Higashi, K Noma, M Yoshizumi, Y Kihara - Circulation journal, 2009 - jstage.jst.go.jp
The vascular endothelium is involved in the release of various vasodilators, including nitric
oxide (NO), prostacyclin and endothelium-derived hyperpolarizing factor, as well as …

The flavonoid biosynthetic pathway in Arabidopsis: structural and genetic diversity

…, R Nakabayashi, Y Higashi… - Plant Physiology and …, 2013 - Elsevier
Flavonoids are representative plant secondary products. In the model plant Arabidopsis
thaliana, at least 54 flavonoid molecules (35 flavonols, 11 anthocyanins and 8 …

Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial

…, D Hart, S Henein, B Herskowitz, S Higashi, Y Higashi… - Jama, 2023 - jamanetwork.com
Importance There are limited efficacious treatments for Alzheimer disease. Objective To assess
efficacy and adverse events of donanemab, an antibody designed to clear brain amyloid …

[HTML][HTML] Endothelial function and oxidative stress in renovascular hypertension

Y Higashi, S Sasaki, K Nakagawa… - … England Journal of …, 2002 - Mass Medical Soc
Background It has been reported that renovascular hypertension activates the renin–angiotensin
system, leading to an increase in oxidative stress. We sought to determine whether …

A lipidome atlas in MS-DIAL 4

…, Y Yamada, I Tada, P Bonini, Y Higashi… - Nature …, 2020 - nature.com
We present Mass Spectrometry-Data Independent Analysis software version 4 (MS-DIAL 4),
a comprehensive lipidome atlas with retention time, collision cross-section and tandem …

Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures

Y Yukimune, H Tabata, Y Higashi, Y Hara - Nature biotechnology, 1996 - nature.com
Taxus cell culture may be an alternative source of paclitaxel and related taxane production.
Significantly increased amounts of paclitaxel and baccatin III were observed in cultured cells …

Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress

C Goto, Y Higashi, M Kimura, K Noma, K Hara… - Circulation, 2003 - Am Heart Assoc
Background— Aerobic exercise enhances endothelium-dependent vasodilation in
hypertensive patients, patients with chronic heart failure, and healthy individuals. However, it is …

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene.

Y Higashi, H Yoshioka, M Yamane… - Proceedings of the …, 1986 - National Acad Sciences
… The presence of a hot spot in this limited region is reminiscent of a recombination point as
suggested with the human fetal y-globin gene (16). In these genetic situations, once one of the …

Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia

Y Higashi, M Kimura, K Hara, K Noma, D Jitsuiki… - Circulation, 2004 - Am Heart Assoc
Background— Patients with limb ischemia were associated with endothelial dysfunction. The
purpose of this study was to determine whether autologous bone-marrow mononuclear cell …