microRNAs (miRNA, miR) play an important role in cancer cell growth and migration;
however, the potential roles of miRNAs in osteosarcoma remain largely uncharacterized. By …

Osteoarthritis is a common cause of functional deterioration in older adults and is an
immense burden on the aging population. Altered chondrogenesis is the most important …

Osteosarcoma is the most common human primary malignant bone tumor in children and
young adults. Sensitive and non-invasive biomarkers that can facilitate disease detection at …

The phenotypic polarization of macrophages are involved in steroid-induced osteonecrosis (ON).
This study tried to investigate the detrimental and beneficial roles of M1/M2 …

Recent studies have revealed that long noncoding RNA metastasis‐associated lung
adenocarcinoma transcript 1 (MALAT1) plays an important role in the development of several solid …

Steroid-induced osteonecrosis of femoral head (ONFH) is a serious complication of
glucocorticoid (GC) use. We investigated the differential expression of miRs in the mesenchymal …

MicroRNAs (miRNAs) have recently been recognized to have a role in human orthopedic
disorders. The objective of our study was to explore the expression profile and biological …

Purpose: To explore potential therapeutic strategies for interrupting the interleukin-6 (IL-6)
signaling pathway, we measured IL-6 expression in ovarian cancer tissues, and evaluated the …

Osteosarcoma is the most common primary malignancy of bone. Patients with localized
disease are routinely treated with surgery and chemotherapy. Unfortunately, many of these …

Bupivacaine is frequently administered for diagnosing and controlling spine-related pain in
interventional spine procedures. However, the potential cytotoxic effects of bupivacaine on …