[HTML][HTML] Osteophytes: relevance and biology
PM Van Der Kraan, WB Van Den Berg - Osteoarthritis and cartilage, 2007 - Elsevier
OBJECTIVE: Osteophytes are common features of osteoarthritis. This review summarizes the
current understanding of the clinical relevance and biology of osteophytes. METHOD: This …
current understanding of the clinical relevance and biology of osteophytes. METHOD: This …
[HTML][HTML] The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models
E Lubberts, MI Koenders, WB van den Berg - Arthritis Res Ther, 2004 - Springer
… Lubberts E, Van den Berg WB, unpublished data). It is of interest that TNF-α-dependent
arthritis can be circumvented by IL-17 (Koenders MI, Lubberts E, Van den Berg WB, unpublished …
arthritis can be circumvented by IL-17 (Koenders MI, Lubberts E, Van den Berg WB, unpublished …
[BOOK][B] The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis
…, C Hughes, B Caterson, WB Van Den Berg - 2012 - academia.edu
… Kraan, PM, Roth, J., van Rooijen, N. & van den Berg WB. (2004) Synovial lining macrophages
mediate osteophyte formation during experimental osteoarthritis. Osteoarthritis and …
mediate osteophyte formation during experimental osteoarthritis. Osteoarthritis and …
Synovial tissue inflammation in early and late osteoarthritis
…, WB Van Den Berg, B Bresnihan - Annals of the …, 2005 - ard.bmj.com
Objective: To compare selected immunohistological features of inflammation in synovial
tissue from patients with early and late osteoarthritis (OA). Methods: Synovial tissue samples …
tissue from patients with early and late osteoarthritis (OA). Methods: Synovial tissue samples …
Treatment with a neutralizing anti‐murine interleukin‐17 antibody after the onset of collagen‐induced arthritis reduces joint inflammation, cartilage destruction, and …
…, LAB Joosten, WB Van Den Berg - … : Official Journal of …, 2004 - Wiley Online Library
Objective Interleukin‐17 (IL‐17) is a proinflammatory cytokine that is expressed in the
synovium of rheumatoid arthritis (RA) patients. This T cell cytokine is implicated in the initiation …
synovium of rheumatoid arthritis (RA) patients. This T cell cytokine is implicated in the initiation …
[PDF][PDF] The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
…, B Van Tits, JA Van Diepen, SAA van den Berg… - Cell metabolism, 2010 - cell.com
Obesity-induced inflammation originating from expanding adipose tissue interferes with
insulin sensitivity. Important metabolic effects have been recently attributed to IL-1β and IL-18, …
insulin sensitivity. Important metabolic effects have been recently attributed to IL-1β and IL-18, …
[HTML][HTML] Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
…, F Ribeiro-Dias, WB Van den Berg - The Journal of …, 2008 - Am Soc Clin Investig
TLRs may contribute to the progression of rheumatoid arthritis through recognition of microbial
or host-derived ligands found in arthritic joints. Here, we show that TLR2 and TLR4, but …
or host-derived ligands found in arthritic joints. Here, we show that TLR2 and TLR4, but …
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis
…, FAJ van de Loo, WB van den Berg - The Journal of …, 2001 - journals.aai.org
T cell IL-17 displays proinflammatory properties and is expressed in the synovium of patients
with rheumatoid arthritis. Its contribution to the arthritic process has not been identified. Here…
with rheumatoid arthritis. Its contribution to the arthritic process has not been identified. Here…
IL-1αβ blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation
…, D Heinegård, WB van den Berg - The Journal of …, 1999 - journals.aai.org
… Wim B. van den Berg … van den Berg; IL-1αβ Blockade Prevents Cartilage and Bone Destruction
in Murine Type II Collagen-Induced Arthritis, Whereas TNF-α Blockade Only Ameliorates …
in Murine Type II Collagen-Induced Arthritis, Whereas TNF-α Blockade Only Ameliorates …
Anticytokine treatment of established type II collagen–induced arthritis in DBA/1 mice: a comparative study using anti‐TNFα, anti–IL‐1α/β, and IL‐1Ra
…, FAJ van de Loo, WB van den Berg - Arthritis & …, 1996 - Wiley Online Library
… van den Bersselaar LAM, van den Hoek AEM, van de Imo AAJ, van den Berg WB: Cationic
immune complex arthritis in mice: a new model. Synergistic effect of complement and …
immune complex arthritis in mice: a new model. Synergistic effect of complement and …