User profiles for William E. Kraus

William E Kraus, MD

Professor of Medicine, Duke University
Verified email at duke.edu
Cited by 60078

Daily energy expenditure through the human life course

…, P Katzmarzyk, KP Kempen, M Kimura, WE Kraus… - Science, 2021 - science.org
Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a
critical variable in human health and physiology, but its trajectory over the life course is poorly …

[HTML][HTML] Genetic and pharmacologic inactivation of ANGPTL3 and cardiovascular disease

…, X Guo, JI Rotter, YDI Chen, WE Kraus… - … England Journal of …, 2017 - Mass Medical Soc
Background Loss-of-function variants in the angiopoietin-like 3 gene (ANGPTL3) have been
associated with decreased plasma levels of triglycerides, low-density lipoprotein (LDL) …

Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial

…, SJ Keteyian, LS Cooper, SJ Ellis, ES Leifer, WE Kraus… - Jama, 2009 - jamanetwork.com
Context Guidelines recommend that exercise training be considered for medically stable
outpatients with heart failure. Previous studies have not had adequate statistical power to …

Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy

…, AM Collinsworth, WM Reichert, WE Kraus… - Journal of …, 2001 - Elsevier
This study evaluated the hypothesis that, due to functional and structural differences, the
apparent elastic modulus and viscous behavior of cardiac and skeletal muscle and vascular …

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

…, H Schunkert, J Erdmann, SH Shah, WE Kraus… - Nature, 2015 - nature.com
Myocardial infarction (MI), a leading cause of death around the world, displays a complex
pattern of inheritance 1 , 2 . When MI occurs early in life, genetic inheritance is a major …

[PDF][PDF] Understanding the cellular and molecular mechanisms of physical activity-induced health benefits

…, RE Gerszten, MP Mattson, RT Hepple, WE Kraus… - Cell metabolism, 2015 - cell.com
The beneficial effects of physical activity (PA) are well documented, yet the mechanisms by
which PA prevents disease and improves health outcomes are poorly understood. To identify …

[HTML][HTML] Effects of the amount and intensity of exercise on plasma lipoproteins

WE Kraus, JA Houmard, BD Duscha… - … England Journal of …, 2002 - Mass Medical Soc
Background Increased physical activity is related to reduced risk of cardiovascular disease,
possibly because it leads to improvement in the lipoprotein profile. However, the amount of …

Regenerating functional myocardium: improved performance after skeletal myoblast transplantation

…, MC Reedy, KA Hutcheson, DD Glower, WE Kraus - Nature medicine, 1998 - nature.com
The adult heart lacks reserve cardiocytes and cannot regenerate. Therefore, a large acute
myocardial infarction often develops into congestive heart failure. To attempt to prevent this …

Interventions to promote physical activity and dietary lifestyle changes for cardiovascular risk factor reduction in adults: a scientific statement from the American Heart …

…, AH Lichtenstein, S Kumanyika, WE Kraus… - Circulation, 2010 - Am Heart Assoc
Approximately 79 400 000 American adults, or 1 in 3, have cardiovascular disease (CVD). 1
CVD accounts for 36.3% or 1 of every 2.8 deaths in the United States and is the leading …

Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE—a randomized controlled study

…, JA Houmard, CW Bales, WE Kraus - Archives of internal …, 2004 - jamanetwork.com
Background Obesity is a major health problem due, in part, to physical inactivity. The amount
of activity needed to prevent weight gain is unknown. Objective To determine the effects of …