Adipokines are proteins produced by white adipose tissue, which is an active secretory organ.
Regulation of immune and inflammatory responses is among the multiple physiological …

Introduction Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease
and is associated with an excess risk of cardiovascular disease. For the general population…

The systemic autoimmune disease rheumatoid arthritis (RA) is characterized by increased
cardiovascular mortality and morbidity and is an independent cardiovascular risk factor. …

Objective: To develop evidence based recommendations for the management of ankylosing
spondylitis (AS) as a combined effort of the ‘ASsessment in AS’ international working group …

Interleukin 6 (IL-6) appears to be a potential mediator of inflammation that may contribute to
the pathogenesis of joint inflammation in RA. Anti-IL-6 monoclonal antibodies (Mab) may …

Background Anti-tumour necrosis factor (TNF) therapy may be associated with opportunistic
infections (OIs). Objective To describe the spectrum of non-tuberculosis OIs associated with …

OBJECTIVES: The French Society of Rheumatology has initiated a large national multicenter,
longitudinal, prospective follow-up of patients presenting with early inflammatory back pain …

Importance One-third of patients with rheumatoid arthritis show inadequate response to tumor
necrosis factor α (TNF-α) inhibitors; little guidance on choosing the next treatment exists. …

Objective To define parameters predictive of lymphoma development in patients with primary
Sjögren's syndrome (SS). Methods A multicenter case–control survey was performed to …

Importance Few treatments are available for patients with glucocorticoid-dependent
polymyalgia rheumatica. IL-6 antagonists may reduce disease activity in patients with active …