… were responsible for reviewing the articles, participated in writing the manuscript, and were
involved in the conception and design of the manuscript; and Drs Schulpen and Kuis were …

Objective. To identify preliminary core sets of outcome variables for disease activity and
damage assessment in juvenile systemic lupus erythematosus (JSLE) and juvenile …

Systemic juvenile idiopathic arthritis (sJIA) is a rare, systemic inflammatory disease classified
as a subtype of JIA. Besides arthritis, it is characterised by systemic features such as …

Background X-linked severe combined immunodeficiency due to a mutation in the gene
encoding the common γ (γc) chain is a lethal condition that can be cured by allogeneic stem-cell …

Cytokines secreted by cells of the immune system can alter the behavior and properties of
immune or other cells. At a site of inflammation, sets of cytokines interact with immune cells, …

Hyperimmunoglobulinaemia D and periodic fever syndrome (HIDS; MIM 260920) is an
autosomal recessive disorder characterized by recurrent episodes of fever associated with …

This study investigates the role of CD4+ CD25+ regulatory T cells during the clinical course
of juvenile idiopathic arthritis (JIA). Persistent oligoarticular JIA (pers-OA JIA) is a subtype of …

Background: Juvenile idiopathic arthritis (JIA) consists of a heterogeneous group of disorders
with, for the most part, an unknown immunopathogenesis. Although onset and disease …

Objective To analyze which physiologic stimuli induce secretion of myeloid‐related protein
8 (MRP8) and MRP14, two S100 proteins expressed in neutrophils and monocytes, and to …

… Patients’ response to sulfasalazine therapy (0) as compared with placebo (W). Response
was defined as improvement in the severity score of joint swelling by 2 grades or a score of 0 …