Objective The 1980 American College of Rheumatology (ACR) classification criteria for
systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present …

Objective To provide a single source for the best available estimates of the national
prevalence of arthritis in general and of selected musculoskeletal disorders (osteoarthritis, …

Background: Survival of scleroderma has changed since the renal crisis treatment has
become possible. Aims: To document the changes in survival and organ system causes of …

Objective To determine the natural history and timing of severe involvement of the kidney,
heart, lung, gastrointestinal (GI) tract, and skin in patients with systemic sclerosis (SSc) and …

… Address reprint requests to Virginia D. Steen, MD, Department of Medicine, 985 Scaife Hall,
University of Pittsburgh School of Medicine, Pittsburgh, PA 15261. Submitted for publication …

OBJECTIVES: To describe the clinical, laboratory, and prognostic features associated with
the scleroderma-specific autoantibodies. METHODS: Using the Pittsburgh Scleroderma …

Background A phase 2 trial of tocilizumab showed preliminary evidence of efficacy in systemic
sclerosis. We assessed skin fibrosis and systemic sclerosis-associated interstitial lung …

Objective. The 1980 American College of Rheuma-tology (ACR) classification criteria for
systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present …

Objective. We sought to identify risk factors for developing severe restrictive lung disease
and to determine the time of onset and rate of progression in patients with systemic sclerosis (…

Objective To determine whether the initiation of corticosteroids or other types of therapy affects
the development of scleroderma renal crisis (SRC). Methods Using a case‐control study, …