2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
…, NS Birnbaum, GR Burmester, VP Bykerk… - Arthritis & …, 2010 - Wiley Online Library
Objective The 1987 American College of Rheumatology (ACR; formerly, the American
Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have been criticized …
Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have been criticized …
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
…, JS Coblyn, SM Helfgott, YC Lee, DJ Todd, VP Bykerk… - Nature, 2017 - nature.com
CD4 + T cells are central mediators of autoimmune pathology; however, defining their key
effector functions in specific autoimmune diseases remains challenging. Pathogenic CD4 + T …
effector functions in specific autoimmune diseases remains challenging. Pathogenic CD4 + T …
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
To define the cell populations that drive joint inflammation in rheumatoid arthritis (RA), we
applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing (…
applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing (…
Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia
…, B Haraoui, GA Mccain, VP Bykerk… - … : Official Journal of …, 1994 - Wiley Online Library
Objective. To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine,
and placebo in the treatment of fibromyalgia, and to identify predictors of response to …
and placebo in the treatment of fibromyalgia, and to identify predictors of response to …
[HTML][HTML] Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
…, GD Kalliolias, SM Goodman, VP Bykerk… - Nature …, 2018 - nature.com
Fibroblasts regulate tissue homeostasis, coordinate inflammatory responses, and mediate
tissue damage. In rheumatoid arthritis (RA), synovial fibroblasts maintain chronic inflammation …
tissue damage. In rheumatoid arthritis (RA), synovial fibroblasts maintain chronic inflammation …
The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: phase 2 methodological report
…, NS Birnbaum, GR Burmester, VP Bykerk… - Arthritis & …, 2010 - Wiley Online Library
Objective The American College of Rheumatology and the European League Against
Rheumatism have developed new classification criteria for rheumatoid arthritis (RA). The aim of …
Rheumatism have developed new classification criteria for rheumatoid arthritis (RA). The aim of …
Canadian Rheumatology Association recommendations for pharmacological management of rheumatoid arthritis with traditional and biologic disease-modifying …
VP Bykerk, P Akhavan, GS Hazlewood… - The Journal of …, 2012 - jrheum.org
Objective. The Canadian Rheumatology Association (CRA) has developed recommendations
for the pharmacological management of rheumatoid arthritis (RA) with traditional and …
for the pharmacological management of rheumatoid arthritis (RA) with traditional and …
[HTML][HTML] Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
…, SM Goodman, LB Ivashkiv, VP Bykerk… - Nature …, 2018 - nature.com
Droplet-based single-cell RNA-seq has emerged as a powerful technique for massively parallel
cellular profiling. While this approach offers the exciting promise to deconvolute cellular …
cellular profiling. While this approach offers the exciting promise to deconvolute cellular …
Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 …
P Emery, GR Burmester, VP Bykerk… - Annals of the …, 2015 - ard.bmj.com
Objectives To evaluate clinical remission with subcutaneous abatacept plus methotrexate (MTX)
and abatacept monotherapy at 12 months in patients with early rheumatoid arthritis (RA)…
and abatacept monotherapy at 12 months in patients with early rheumatoid arthritis (RA)…
[HTML][HTML] Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation
and destruction 1 . There is currently no cure for rheumatoid arthritis, and the effectiveness of …
and destruction 1 . There is currently no cure for rheumatoid arthritis, and the effectiveness of …