Acute kidney injury (AKI) is a global health challenge of vast proportions, as approx. 13.3%
of people worldwide are affected annually. The pathophysiology of AKI is very complex, but …

Objective Abnormalities in haematological parameters have been noted in patients with
thyroid diseases. Nevertheless, the exact mechanism of thyroid hormones' (THs) action on …

Purinergic signalling plays a crucial role in proper functioning of the nervous system. Mechanisms
depending on extracellular nucleotides and their P2 receptors also underlie a number …

Favipiravir (FPV) is a novel antiviral drug acting as a competitive inhibitor of RNA-dependent
RNA polymerase (RdRp), preventing viral transcription and replication. FPV was approved …

Purpose Gestational diabetes mellitus (GDM) is the glucose intolerance occurring during
pregnancy. The prevalence of GDM is increased in obese women. Leptin and adiponectin are …

Adiponectin is the adipokine associated with insulin sensitization, reducing liver gluconeogenesis,
and increasing fatty acid oxidation and glucose uptake. Adiponectin is present in the …

Aim: Recent findings suggest that chronic inflammatory processes play a role in the progression
of age-related macular degeneration (AMD). Here we asked whether the development …

Gestational diabetes mellitus (GDM) is glucose intolerance detected during pregnancy. The
MTNR1B gene is the genetic locus associated with type 2 diabetes, that may affect insulin …

Renal transplantation is now the best treatment for end-stage renal failure. To avoid
rejection and prolong graft function, organ recipients need immunosuppressive therapy. The …

Connexins (Cx) are members of a protein family that forms intercellular channels localised in
gap junction (GJ) plaques and single transmembrane channels called hemichannels. They …