To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis
of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped …

Psoriasis and Psoriatic Arthritis (PsA) are chronic inflammatory diseases that have a major
impact on health. The prevalence and incidence estimates of these two closely related …

Psoriasis is a common inflammatory disorder of the skin and other organs. We have determined
that mutations in CARD14, encoding a nuclear factor of kappa light chain enhancer in B …

Objective To determine whether the presence of psoriatic arthritis (PsA) is associated with
greater comorbidity, in particular cardiovascular morbidity, compared to psoriasis without …

Psoriasis vulgaris (PsV) is a common inflammatory and hyperproliferative skin disease. Up
to 30% of people with PsV eventually develop psoriatic arthritis (PsA), an inflammatory …

Background This investigation aimed to determine whether patients presenting to a
psoriatic arthritis (PsA) clinic early in the course of the disease had less severe disease at …

Objective. Biomarkers may be helpful in screening patients with psoriasis for PsA. Our purpose
was to identify serum biomarkers for psoriasis and PsA. Methods. Fifty-two patients with …

Genetic epidemiological studies have demonstrated a significant genetic basis to both psoriasis
and psoriatic arthritis (PsA). Although candidate gene association studies had identified …

Psoriasis is a complex disease of skin with a prevalence of about 2%. We conducted the
largest meta-analysis of genome-wide association studies (GWAS) for psoriasis to date, …

Objective To estimate the incidence of psoriatic arthritis (PsA) in patients with psoriasis, and
to identify risk factors for its development. Methods The study was designed as a prospective …