[HTML][HTML] Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

…, D Mauri, D Cavill, TP Gordon… - The Journal of …, 2002 - Am Soc Clin Investig
BAFF (BLyS, TALL-1, THANK, zTNF4) is a member of the TNF superfamily that specifically
regulates B lymphocyte proliferation and survival. Mice transgenic (Tg) for BAFF develop an …

[HTML][HTML] Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

…, HE Kent, FL Mordant, TE Schlub, DL Gordon… - Nature …, 2021 - nature.com
The durability of infection-induced SARS-CoV-2 immunity has major implications for reinfection
and vaccine development. Here, we show a comprehensive profile of antibody, B cell …

Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome

SA Waterman, TP Gordon… - Arthritis & Rheumatism …, 2000 - Wiley Online Library
Objective Sjögren's syndrome (SS) is an autoimmune disorder characterized by dry eyes
and mouth (sicca syndrome) and lymphocytic infiltration of the lacrimal and salivary glands. …

[HTML][HTML] Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and-SSB/La antibodies in the pathogenesis of congenital heart block

…, F Nimmerjahn, TP Gordon… - The Journal of …, 2006 - Am Soc Clin Investig
The role of cardiocytes in physiologic removal of apoptotic cells and the subsequent effect of
surface binding by anti-SSA/Ro and -SSB/La antibodies was addressed. Initial experiments …

The BAFF/APRIL system: an important player in systemic rheumatic diseases

F Mackay, F Sierro, ST Grey, TP Gordon - B Cell Trophic Factors and B …, 2005 - karger.com
Many rheumatic diseases have an autoimmune basis, characterized by organ-specific
inflammation and tissue destruction. Diseases such as rheumatoid arthritis, systemic lupus …

Antibody-mediated gastrointestinal dysmotility in scleroderma

F Goldblatt, TP Gordon, SA Waterman - Gastroenterology, 2002 - Elsevier
Background & Aims: Defects in enteric excitatory neurotransmission have been proposed to
underlie the gastrointestinal dysmotility associated with scleroderma (systemic sclerosis). …

[PDF][PDF] Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody

…, D Christ, R Brink, F Luciani, TP Gordon… - Cell, 2020 - cell.com
Pathogenic autoantibodies arise in many autoimmune diseases, but it is not understood how
the cells making them evade immune checkpoints. Here, single-cell multi-omics analysis …

Subcellular distribution of aquaporin 5 in salivary glands in primary Sjögren's syndrome

…, J Hiscock, R Jonsson, SA Waterman, TP Gordon - The Lancet, 2001 - thelancet.com
Secretions from salivary and lacrimal glands are reduced in patients with primary Sjögren's
syndrome (PSS). Since aquaporin 5 is involved in transport of water and is present in …

[HTML][HTML] Selective down-regulation of aquaporin-1 in salivary glands in primary Sjögren's syndrome

…, J Hiscock, BJ Gannon, R Jonsson, TP Gordon… - Laboratory …, 2002 - Elsevier
Salivary and lacrimal gland secretions are reduced in primary Sjögren's syndrome (pSS).
Aquaporins (AQPs) are involved in transmembrane water transport, and different isoforms …

Aggression and social controls in rhesus monkey (Macaca mulatta) groups revealed in group formation studies

IS Bernstein, TP Gordon, RM Rose - Folia primatologica, 1974 - brill.com
Agonistic responses were the primary form of social interaction during five rhesus group
formations. Males showed the most extreme forms of aggression initially, but as formative …