[HTML][HTML] Identification of late-onset hypogonadism in middle-aged and elderly men

…, SR Pye, AJ Silman, JD Finn, TW O'Neill… - … England Journal of …, 2010 - Mass Medical Soc
Background The association between aging-related testosterone deficiency and late-onset
hypogonadism in men remains a controversial concept. We sought evidence-based criteria …

Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study

…, SR Pye, AJ Silman, JD Finn, TW O'Neill… - The Journal of …, 2008 - academic.oup.com
Context: The cause of declining testosterone (T) in aging men and their relationships with
risk factors are unclear. Objective: The objective of the study was to investigate the …

Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study

A Tajar, G Forti, TW O'Neill, DM Lee… - The Journal of …, 2010 - academic.oup.com
Context: The diagnosis of late-onset hypogonadism (LOH) in older men with age-related
declines in testosterone (T) is currently not well characterized. Objective: Our objective was to …

Postmenopausal osteoporosis

R Eastell, TW O'Neill, LC Hofbauer… - Nature reviews Disease …, 2016 - nature.com
Osteoporosis is a metabolic bone disorder that is characterized by low bone mass and micro-architectural
deterioration of bone tissue. Fractures of the proximal femur, the vertebrae and …

A meta‐analysis of the association of fracture risk and body mass index in women

…, D Mellström, LJ Melton III, TW O'Neill… - … of bone and mineral …, 2014 - academic.oup.com
Several recent studies suggest that obesity may be a risk factor for fracture. The aim of this
study was to investigate the association between body mass index (BMI) and future fracture …

Age-related changes in general and sexual health in middle-aged and older men: results from the European Male Ageing Study (EMAS)

…, DB O'Connor, M Maggi, TW O'Neill… - The journal of sexual …, 2010 - academic.oup.com
Introduction Limited information is available concerning the general and sexual health status
of European men. Aim To investigate the age-related changes in general and sexual health …

Update on the epidemiology, risk factors and disease outcomes of osteoarthritis

TW O'Neill, PS McCabe, J McBeth - Best practice & research Clinical …, 2018 - Elsevier
Osteoarthritis (OA) is the most frequent form of arthritis and a leading cause of pain and
disability worldwide. OA can affect any synovial joint, although the hip, knee, hand, foot and …

Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS)

A Tajar, IT Huhtaniemi, TW O'Neill… - The Journal of …, 2012 - academic.oup.com
Context: Late-onset hypogonadism (LOH) has been defined as a syndrome in middle-aged
and elderly men reporting symptoms in the presence of low testosterone (T). Objective: The …

Determinants of incident vertebral fracture in men and women: results from the European Prospective Osteoporosis Study (EPOS)

DK Roy, TW O'Neill, JD Finn, M Lunt, AJ Silman… - Osteoporosis …, 2003 - Springer
The aim of this analysis was to determine the influence of lifestyle, anthropometric and
reproductive factors on the subsequent risk of incident vertebral fracture in men and women aged …

Association of hypogonadism with vitamin D status: the European Male Ageing Study

…, R Bouillon, TW O'Neill… - European journal of …, 2012 - academic.oup.com
Objective Interrelationships between hormones of the hypothalamic–pituitary–testicular (HPT)
axis, hypogonadism, vitamin D and seasonality remain poorly defined. We investigated …