The role of inflammation in epilepsy
Epilepsy is the third most common chronic brain disorder, and is characterized by an enduring
predisposition to generate seizures. Despite progress in pharmacological and surgical …
predisposition to generate seizures. Despite progress in pharmacological and surgical …
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
…, XJ Xu, Z Wiesenfeld-Hallin, T Hökfelt, T Bartfai… - Nature …, 1998 - nature.com
Peptide nucleic acids (PNAs) form stable and tight complexes with complementary DNA and/or
RNA and would be promising antisense reagents if their cellular delivery could be …
RNA and would be promising antisense reagents if their cellular delivery could be …
Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section
XJ Xu, JX Hao, S Andell-Jonsson, V Poli, T Bartfai… - Cytokine, 1997 - Elsevier
The cutaneous nociceptive response threshold to mechanical and thermal stimulation, the
development of hyperalgesia and plasma extravasation after subcutaneous injection of …
development of hyperalgesia and plasma extravasation after subcutaneous injection of …
Interleukin‐1β contributes to the generation of experimental febrile seizures
…, A Vezzani, M Behrens, T Bartfai… - Annals of Neurology …, 2005 - Wiley Online Library
Fever can provoke “febrile” seizures (FS). Because complex FS may promote development
of temporal lobe epilepsy, understanding their mechanisms is clinically important. Using an …
of temporal lobe epilepsy, understanding their mechanisms is clinically important. Using an …
[HTML][HTML] A blood based 12-miRNA signature of Alzheimer disease patients
Background Alzheimer disease (AD) is the most common form of dementia but the identification
of reliable, early and non-invasive biomarkers remains a major challenge. We present a …
of reliable, early and non-invasive biomarkers remains a major challenge. We present a …
[PDF][PDF] Cytokines and fever
B Conti, I Tabarean, C Andrei, T Bartfai - Front Biosci, 2004 - researchgate.net
… are the findings that cell penetrating ceramide analogs such as C2 ceramide can in vivo
mediate fever like rise in temperature when applied intracerebroventricularly (Bartfai et al., …
mediate fever like rise in temperature when applied intracerebroventricularly (Bartfai et al., …
IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures
…, M Maroso, S Balosso, MA Sanchez, T Bartfai - Brain, behavior, and …, 2011 - Elsevier
Increasing evidence supports the involvement of immune and inflammatory processes in
the etiopathogenesis of seizures. In particular, activation of innate immune mechanisms and …
the etiopathogenesis of seizures. In particular, activation of innate immune mechanisms and …
Transgenic mice with a reduced core body temperature have an increased life span
Reduction of core body temperature has been proposed to contribute to the increased life
span and the antiaging effects conferred by calorie restriction (CR). Validation of this …
span and the antiaging effects conferred by calorie restriction (CR). Validation of this …
VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier functions
A Elmquist, M Lindgren, T Bartfai, Ü Langel - Experimental cell research, 2001 - Elsevier
Cell-penetrating peptides, CPPs, have been shown to translocate into living cells by a
receptor-independent mechanism and to carry macromolecules over the plasma membrane. This …
receptor-independent mechanism and to carry macromolecules over the plasma membrane. This …
Neuropeptides: opportunities for drug discovery
T Hökfelt, T Bartfai, F Bloom - The Lancet Neurology, 2003 - thelancet.com
The role of peptides as signalling molecules in the nervous system has been studied for more
than 30 years. Neuropeptides and their G-protein-coupled receptors are widely distributed …
than 30 years. Neuropeptides and their G-protein-coupled receptors are widely distributed …