User profiles for Takashi Inui

Takashi Inui

- Verified email at omu.ac.jp - Cited by 3691

Takashi INUI

- Verified email at cs.tsukuba.ac.jp - Cited by 1604

[PDF][PDF] Extracting semantic orientations of words using spin model

H Takamura, T Inui, M Okumura - … of the 43rd Annual Meeting of …, 2005 - aclanthology.org
We propose a method for extracting semantic orientations of words: desirable or undesirable.
Regarding semantic orientations as spins of electrons, we use the mean field …

A toxic monomeric conformer of the polyglutamine protein

Y Nagai, T Inui, HA Popiel, N Fujikake… - Nature structural & …, 2007 - nature.com
Polyglutamine (polyQ) diseases are classified as conformational neurodegenerative
diseases, like Alzheimer and Parkinson diseases, and they are caused by proteins with an …

[HTML][HTML] The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell …

…, A Fujita, A Fukuhara, YT Azuma, F Hata, T Inui… - Journal of Biological …, 2007 - ASBMB
Recent studies have revealed that the redox-sensitive glycolytic enzyme, glyceraldehyde-3-phosphate
dehydrogenase (GAPDH), is involved in neuronal cell death that is triggered by …

Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher

…, H Taniguchi, T Kanekiyo, K Aritake, T Inui… - Journal of …, 2006 - Soc Neuroscience
Prostaglandin (PG) D 2 is well known as a mediator of inflammation. Hematopoietic PGD
synthase (HPGDS) is responsible for the production of PGD 2 involved in inflammatory …

A potent and specific agonist, Suc-[Glu9, Ala11, 15]-endothelin-1 (8-21), IRL 1620, for the ETB receptor

…, T Watakabe, Y Fujitani, K Oda, Y Urade, T Inui… - Biochemical and …, 1992 - Elsevier
A series of C-terminal linear peptides of endothelin (ET)-1 and their N α -succinyl (Suc)
analogs were synthesized and their binding affinities for the two subtypes of ET receptor, ET A …

[HTML][HTML] Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death

…, H Ihara, YT Azuma, H Tajima, T Inui… - Journal of Biological …, 2009 - ASBMB
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) 2 2The abbreviations used are:
GAPDHglyceraldehyde-3-phosphate dehydrogenaseNOR3(±)-(E)-4-ethyl-2-[(E)-hydroxyimino]-…

Identification of a Novel Prostaglandin F Synthase in Trypanosoma brucei

…, M Rawer, A Szallies, K Fujimori, T Inui… - The Journal of …, 2000 - rupress.org
Members of the genus Trypanosoma cause African trypanosomiasis in humans and animals
in Africa. Infection of mammals by African trypanosomes is characterized by an upregulation …

Doxorubicin-conjugated dendrimer/collagen hybrid gels for metastasis-associated drug delivery systems

…, A Fukuhara, E Nishisaka, A Harada, K Kono, T Inui… - Acta biomaterialia, 2013 - Elsevier
Metastasis is a characteristic property of cancer cells, which degrade extracellular matrix
containing collagen. We prepared a polymer prodrug-embedded collagen gel for metastasis-…

[HTML][HTML] High titers of both rheumatoid factor and anti-CCP antibodies at baseline in patients with rheumatoid arthritis are associated with increased circulating …

T Takeuchi, N Miyasaka, T Inui, T Yano… - Arthritis research & …, 2017 - Springer
Background Although both rheumatoid factor (RF) and anticyclic citrullinated peptide
antibodies (anti-CCP) are useful for diagnosing rheumatoid arthritis (RA), the impact of these …

[HTML][HTML] Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption

T Inui, O Ishibashi, T Inaoka, Y Origane… - Journal of Biological …, 1997 - ASBMB
Cathepsin K is a recently identified cysteine protease which is abundantly and selectively
expressed in osteoclasts. To evaluate the contribution of cathepsin K to bone resorption …