Increased excretions of β2-microglobulin, IL-6, and IL-8 and decreased excretion of Tamm-Horsfall glycoprotein in urine of patients with active lupus nephritis

CY Tsai, TH Wu, CL Yu, JY Lu, YY Tsai - Nephron, 2000 - karger.com
Tubulointerstitial nephritis is a less frequently recognized but important complication of systemic
lupus erythematosus. We have investigated the cytokine β 2-microglobulin (β 2 M) and …

Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis

HT Lee, YM Shiao, TH Wu, WS Chen, YH Hsu… - The Journal of …, 2010 - jrheum.org
Objective. Systemic lupus erythematosus (SLE) is a prototype of systemic autoimmune disease
in which cytokines such as B lymphocyte chemoattractant (BLC, or CXC motif ligand 13, …

The pathogenesis of systemic lupus erythematosus-From the viewpoint of oxidative stress and mitochondrial dysfunction

HT Lee, TH Wu, CS Lin, CS Lee, YH Wei, CY Tsai… - Mitochondrion, 2016 - Elsevier
SLE is characterized by an increased production of detrimental autoantigens, exaggerated
effects of pro-inflammatory cytokines, dysregulated functioning of immunocompetent cells …

[HTML][HTML] Tamm–Horsfall protein is a potent immunomodulatory molecule and a disease biomarker in the urinary system

TH Wu, KJ Li, CL Yu, CY Tsai - Molecules, 2018 - mdpi.com
Tamm–Horsfall protein (THP), or uromodulin (UMOD), is an 80–90-kDa phosphatidylinositol-anchored
glycoprotein produced exclusively by the renal tubular cells in the thick …

An open‐label, crossover study of a new phosphate‐binding agent in haemodialysis patients: ferric citrate

WC Yang, CS Yang, CC Hou, TH Wu… - Nephrology Dialysis …, 2002 - academic.oup.com
Background. Hyperphosphataemia contributes to secondary hyperparathyroidism and renal
osteodystrophy in patients with end‐stage renal disease (ESRD). Calcium salts are widely …

[HTML][HTML] Cross-talk between mitochondrial dysfunction-provoked oxidative stress and aberrant noncoding RNA expression in the pathogenesis and pathophysiology of …

…, SC Hsieh, CS Lu, TH Wu, HT Liao, CH Wu… - International Journal of …, 2019 - mdpi.com
Systemic lupus erythematosus (SLE) is a prototype of systemic autoimmune disease involving
almost every organ. Polygenic predisposition and complicated epigenetic regulations are …

Risk management of wind farm micro-siting using an enhanced genetic algorithm with simulation optimization

PY Yin, TH Wu, PY Hsu - Renewable Energy, 2017 - Elsevier
Wind farm micro-siting is the decision problem for determining the optimal placement of wind
turbines in consideration of the wake effect. Existing micro-siting models seek to minimize …

[HTML][HTML] Decipher the immunopathological mechanisms and set up potential therapeutic strategies for patients with lupus nephritis

…, KJ Li, CY Shen, CH Lu, HT Lee, TH Wu… - International Journal of …, 2023 - mdpi.com
Lupus nephritis (LN) is one of the most severe complications in patients with systemic lupus
erythematosus (SLE). Traditionally, LN is regarded as an immune complex (IC) deposition …

Increased excretion of tumor necrosis factor alpha and interleukin 1 β in urine from patients with IgA nephropathy and Schönlein-Henoch purpura

TH Wu, SC Wu, TP Huang, CL Yu, CY Tsai - Nephron, 1996 - karger.com
Urinary proteins (5 mg/ml) collected from a group of 16 patients including 13 with IgA nephropathy
and 3 with Schönlein-Henoch purpura (SHP) and from a control group consisting of 6 …

Survival analysis in systemic lupus erythematosus patients on maintenance dialysis: a nationwide population-based study in Taiwan

YS Chang, CJ Liu, TH Wu, CH Chaou, KC Lin… - …, 2013 - academic.oup.com
Objectives. This study aimed to identify the risk factors for mortality and the impact of dialysis
modalities on the survival in SLE patients with end-stage renal disease (ESRD). Methods. …