Background: Mikulicz’s disease (MD) has been considered as one manifestation of Sjögren’s
syndrome (SS). Recently, it has also been considered as an IgG 4 -related disorder. …

IgG4-related disease is a recently recognized multi-organ disorder characterized by high
levels of serum IgG4 and dense infiltration of IgG4-positive cells into several organs. Although …

Objective. Interstitial lung disease (ILD), especially rapidly progressive ILD (RPILD), is a
major poor prognostic factor in patients with DM. We investigated the association of anti-…

Objectives We investigated the relationships among M1 monocytes, M2 monocytes, osteoclast
(OC) differentiation ability, and clinical characteristics in patients with rheumatoid arthritis (…

IgG4-related disease is a new disease classification established in Japan in the 21st century.
Patients with IgG4-related disease display hyper-IgG4-gammaglobulinemia, massive …

Serum amyloid A (SAA) is a precursor protein for amyloid A, which is a constituent for amyloid
fibrils in secondary amyloidosis. To determine the role of SAA in the articular destruction in …

Objective To evaluate whether magnetic resonance imaging (MRI) of the wrists and finger
joints and an analysis of serologic autoantibodies are clinically meaningful for the subsequent …

We investigated the effects of anti-IL-6 receptor antibody, tocilizumab (TCZ), on lipid metabolism.
Nineteen patients with rheumatoid arthritis (RA), entered in clinical case–control study …

Objective. To investigate whether the frequency of peripheral blood (PB) regulatory T cells (Treg)
correlates with the clinical disease activity of rheumatoid arthritis (RA). Methods. PB …

Objective Takayasu arteritis (TAK) is a systemic vasculitis affecting large arteries and large
branches of the aorta. Ulcerative colitis (UC) is a prevalent autoimmune colitis. Since TAK …