Background— CD40L-CD40 interactions induce inflammatory signals in cells of the vascular
wall. We evaluated the effects of glycoprotein (GP) IIb/IIIa (α IIb β 3 ) engagement that …

Objective: Inflammatory conditions contribute to increased expression of various activity markers
in platelets and endothelial cells, leading to atherosclerotic changes in the vascular wall…

Fibrinogen concentration influences mechanical and functional properties of the clot. The
purpose of the present study was to identify threshold concentrations of fibrinogen resulting in …

Background: In addition to their cholesterol lowering ability, statins have proven pleiotropic
effects in the cardiovascular system. Chronic inflammation with interactions between platelets …

Aims Chronic inflammation is a major contributing factor to atherosclerosis and various markers
of inflammation, fibrinolysis and coagulation are upregulated in patients with established …

Objective. Since Wegener’s granulomatosis (WG) represents a relapsing disease, efforts
have been made to reliably predict relapses using blood tests. Followup measures such as …

Background: Atherosclerotic plaques prone to cause thrombotic complications and plaque
rupture account for the majority of fatal myocardial infarctions (MI), which may be complicated …

Background and aims The CD40 − CD40 Ligand (CD40L) system has an important role in
vascular inflammation. For this reason, we assessed the association of soluble CD40L with …

Patients with Takotsubo cardiomyopathy (TC) often present with symptoms similar to those
of myocardial infarction (MI). We analyzed blood concentrations of mediators of inflammation …

Background: An important role in the acceleration of vascular disease has been previously
suggested for advanced glycation end products. N ε -(carboxymethyl)lysine (CML) is an …