[HTML][HTML] Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised …
B Williams, TM MacDonald, S Morant, DJ Webb… - The Lancet, 2015 - thelancet.com
Background Optimal drug treatment for patients with resistant hypertension is undefined. We
aimed to test the hypotheses that resistant hypertension is most often caused by excessive …
aimed to test the hypotheses that resistant hypertension is most often caused by excessive …
Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease
Background: Glucocorticoids have adverse systemic effects, including obesity, hypertension,
and hyperglycemia, that may predispose to cardiovascular disease. The effect of …
and hyperglycemia, that may predispose to cardiovascular disease. The effect of …
Adherence to insulin treatment, glycaemic control, and ketoacidosis in insulin-dependent diabetes mellitus
…, DIR Boyle, AD McMahon, SA Greene, TM MacDonald… - The Lancet, 1997 - thelancet.com
Background Intensive insulin treatment effectively delays the onset and slows the progression
of microvascular complications in insulin-dependent diabetes mellitus (IDDM). Variable …
of microvascular complications in insulin-dependent diabetes mellitus (IDDM). Variable …
Adherence to prescribed oral hypoglycaemic medication in a population of patients with Type 2 diabetes: a retrospective cohort study
PT Donnan, TM MacDonald, AD Morris - Diabetic Medicine, 2002 - Wiley Online Library
Aims To evaluate the patterns and predictors of adherence in all patients with Type 2 diabetes
in the community receiving treatment with a single oral hypoglycaemic drug. In particular, …
in the community receiving treatment with a single oral hypoglycaemic drug. In particular, …
Socio‐economic status, obesity and prevalence of Type 1 and Type 2 diabetes mellitus
…, RW Newton, DA Ruta, TM MacDonald… - Diabetic …, 2000 - Wiley Online Library
Aims The influence of socio‐economic status on the prevalence of Type 1 and Type 2 diabetes
mellitus, and on obesity, was explored using routinely collected healthcare data for the …
mellitus, and on obesity, was explored using routinely collected healthcare data for the …
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study
N Tzemos, PO Lim, TM MacDonald - Circulation, 2001 - Am Heart Assoc
Background Vascular endothelial dysfunction may predict future atherosclerosis. Hence, an
antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure …
antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure …
Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy
…, SR Bonellie, RT Jung, TM MacDonald… - The Journal of …, 2010 - academic.oup.com
Context: For patients on T 4 replacement, the dose is guided by serum TSH concentrations,
but some patients request higher doses due to adverse symptoms. Objective: The aim of the …
but some patients request higher doses due to adverse symptoms. Objective: The aim of the …
[HTML][HTML] Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective …
…, AD Struthers, CC Lang, TM MacDonald - The Lancet, 2022 - thelancet.com
Background Studies have suggested that evening dosing with antihypertensive therapy
might have better outcomes than morning dosing. The Treatment in Morning versus Evening (…
might have better outcomes than morning dosing. The Treatment in Morning versus Evening (…
Review of aldosterone-and angiotensin II-induced target organ damage and prevention
AD Struthers, TM MacDonald - Cardiovascular research, 2004 - academic.oup.com
Aldosterone is well recognized as a cause of sodium reabsorption, water retention, and
potassium and magnesium loss; however, it also produces a variety of other actions that lead to …
potassium and magnesium loss; however, it also produces a variety of other actions that lead to …
Frequency of blood glucose monitoring in relation to glycaemic control: observational study with diabetes database
Objectives: To investigate patterns of self monitoring of blood glucose concentration in diabetic
patients who use insulin and to determine whether frequency of self monitoring is related …
patients who use insulin and to determine whether frequency of self monitoring is related …