Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis
…, Y Kamata, K Nagatani, T Nagashima… - The Journal of …, 2010 - jrheum.org
Objective. To determine levels of interleukin 33 (IL-33) in serum and synovial fluid (SF) and
their clinical associations in patients with rheumatoid arthritis (RA). To evaluate the ability of …
their clinical associations in patients with rheumatoid arthritis (RA). To evaluate the ability of …
Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis
T Nagashima, H Okazaki, K Yudoh… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To determine whether statins induce apoptosis in rheumatoid arthritis (RA)
synoviocytes. Methods The effects of lipophilic and hydrophilic statins (fluvastatin and pravastatin, …
synoviocytes. Methods The effects of lipophilic and hydrophilic statins (fluvastatin and pravastatin, …
Reactivation of hepatitis B virus in rheumatoid arthritis patients treated with biological disease‐modifying antirheumatic drugs
J Nakamura, T Nagashima, K Nagatani… - … journal of rheumatic …, 2016 - Wiley Online Library
Objective To examine the incidence of hepatitis B virus ( HBV ) reactivation in patients with
rheumatoid arthritis ( RA ) receiving biological disease‐modifying antirheumatic drugs ( …
rheumatoid arthritis ( RA ) receiving biological disease‐modifying antirheumatic drugs ( …
Glucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumab
K Matsumoto, T Nagashima, S Takatori… - Clinical …, 2009 - Springer
We report a 29-year-old Japanese woman with disseminated intravascular coagulation (DIC)
and adult onset Still’s disease (AOSD). Her disease was refractory to high-dose …
and adult onset Still’s disease (AOSD). Her disease was refractory to high-dose …
Safety and tolerability of anifrolumab, a monoclonal antibody targeting type I interferon receptor, in Japanese patients with systemic lupus erythematosus: a multicenter …
…, T Ishii, H Nakajima, S Kawai, T Nagashima… - Modern …, 2020 - academic.oup.com
Objectives: This study evaluated the safety and tolerability of anifrolumab, a monoclonal
antibody targeting the type I interferon (IFN) receptor, in Japanese patients with moderate-to-…
antibody targeting the type I interferon (IFN) receptor, in Japanese patients with moderate-to-…
Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible …
…, S Onishi, Y Kamata, K Nagatani, T Nagashima… - Rheumatology …, 2012 - Springer
Although TNF inhibitors have dramatically improved the outcome of patients with rheumatoid
arthritis, 30–40% of patients do not respond well to them and treatment needs to be …
arthritis, 30–40% of patients do not respond well to them and treatment needs to be …
Liver dysfunction in anti-melanoma differentiation-associated gene 5 antibody-positive patients with dermatomyositis
T Nagashima, Y Kamata, M Iwamoto, H Okazaki… - Rheumatology …, 2019 - Springer
The objective was to investigate the clinical and histological features of liver dysfunction in
patients with polymyositis (PM) or dermatomyositis (DM).A total of 115 patients (38 with PM …
patients with polymyositis (PM) or dermatomyositis (DM).A total of 115 patients (38 with PM …
Successful treatment of a patient with rheumatoid arthritis and IgA-kappa multiple myeloma with tocilizumab
Y Matsuyama, T Nagashima, K Honne, Y Kamata… - Internal …, 2011 - jstage.jst.go.jp
A 63-year-old woman receiving tumor necrosis factor (TNF) inhibitors for rheumatoid arthritis
(RA) was found to have smoldering IgA-kappa type multiple myeloma (MM). Retrospective …
(RA) was found to have smoldering IgA-kappa type multiple myeloma (MM). Retrospective …
Prognostic indicators related to death in patients with Pneumocystis pneumonia associated with collagen vascular diseases
Y Aoki, M Iwamoto, Y Kamata, T Nagashima… - Rheumatology …, 2009 - Springer
The objective of this study is to investigate the clinical markers of life-threatening Pneumocystis
pneumonia (PCP) in patients with collagen vascular diseases (CVD). The patients who …
pneumonia (PCP) in patients with collagen vascular diseases (CVD). The patients who …
Unchanged serum viral load and liver function during tocilizumab treatment in a patient with rheumatoid arthritis and hepatitis C virus infection
T Nagashima, A Maruyama, Y Kamata… - Rheumatology …, 2012 - Springer
Treatment of rheumatoid arthritis (RA) with biological agents in patients who have viral hepatitis
is problematic and difficult. So far, little is known about the safety of tocilizumab (TCZ), an …
is problematic and difficult. So far, little is known about the safety of tocilizumab (TCZ), an …