Recent studies have shown that cellular metabolism plays an important role in regulating
immune cell functions. In immune cell differentiation, both interleukin-17-producing T (Th17) …

Background The recent findings of cancer-specific metabolic changes, including increased
glucose and glutamine consumption, have provided new therapeutic targets for consideration…

Resolvins, are specialized pro-resolving mediators (SPMs) derived from n-3 polyunsaturated
fatty acids. They contribute actively to the resolution of inflammation, but little is known …

Recent studies have revealed a relationship between cellular metabolism and cell function
in immune cells. Cellular metabolism not only provides supplemental ATP, but also supports …

Objectives Exosomes are potent vehicles for intercellular communication. Rheumatoid
arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 …

Objective SKG mice develop interstitial lung disease ( ILD ) resembling rheumatoid arthritis–associated
ILD in humans. The aim of this study was to clarify the mechanism underlying the …

Objectives This multicentre retrospective study in Japan aimed to assess the retention of
biological disease-modifying antirheumatic drugs and Janus kinase inhibitors (JAKi), and to …

Background Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue
disorder. Although the etiology of the disease remains undetermined, SSc is characterized by …

Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated
cooperatively in the differentiation and activation of inflammatory immune cells. But the …

An 80-year-old woman with rheumatoid arthritis presented with chest pain. Clinical examination
revealed new-onset paroxysmal atrial fibrillation with symptomatic sinus pauses and …