We isolated the human adipose-specific and most abundant gene transcript, apM1 (Maeda,
K., et al.,Biochem. Biophys. Res. Commun.221, 286–289, 1996). The apM1 gene product …

Adiponectin is a novel, adipose-specific protein abundantly present in the circulation, and it
has antiatherogenic properties. We analyzed the plasma adiponectin concentrations in age- …

Background—Among the many adipocyte-derived endocrine factors, we recently found an
adipocyte-specific secretory protein, adiponectin, which was decreased in obesity. Although …

Background—Among the many adipocyte-derived endocrine factors, we found an adipocyte-derived
plasma protein, adiponectin, that was decreased in obesity. We recently …

Insulin resistance and its dreaded consequence, type 2 diabetes, are major causes of
atherosclerosis. Adiponectin is an adipose-specific plasma protein that possesses anti-…

Background— Adiponectin is an adipocyte-derived plasma protein that accumulates in the
injured artery and has potential antiatherogenic properties. This study was designed to …

Olfactory transduction is thought to be initiated by the binding of odorants to specific receptor
proteins in the cilia of olfactory receptor cells (reviewed in refs 1–3 ). The mechanism by …

Background— High-sensitive C-reactive protein (hs-CRP) is a well-known risk factor for
coronary artery disease (CAD). Recently, we have demonstrated that adiponectin served as an …

The presence of obesity increases the risk of thrombotic vascular diseases. The role of fat
accumulation and its effect on plasminogen activator inhibitor–1 (PAI–1) levels was …

The treatment of ischemic strokes is limited to prophylactic agents that block the coagulation
cascade. Here, we show that cholesterol-lowering agents, 3-hydroxy-3-methylglutaryl (HMG)…