Influence of obstructive sleep apnea on mortality in patients with heart failure
…, JD Parker, GE Newton, JS Floras, S Mak… - Journal of the American …, 2007 - jacc.org
Objectives : This study sought to determine, in patients with heart failure (HF), whether untreated
moderate to severe obstructive sleep apnea (OSA) is associated with a higher mortality …
moderate to severe obstructive sleep apnea (OSA) is associated with a higher mortality …
Tissue expression and immunolocalization of tumor necrosis factor-α in postinfarction dysfunctional myocardium
MW Irwin, S Mak, DL Mann, R Qu, JM Penninger… - Circulation, 1999 - Am Heart Assoc
Background—Tumor necrosis factor-α (TNF-α) is markedly elevated in advanced heart
failure. It is not known whether tissue TNF-α is elevated in the common setting of myocardial …
failure. It is not known whether tissue TNF-α is elevated in the common setting of myocardial …
Nocturnal rostral fluid shift: a unifying concept for the pathogenesis of obstructive and central sleep apnea in men with heart failure
…, MC Su, S Smith, GE Newton, S Mak… - Circulation, 2010 - Am Heart Assoc
Background— Obstructive sleep apnea (OSA) and central sleep apnea are common in
patients with heart failure. We hypothesized that in such patients, severity of OSA is related to …
patients with heart failure. We hypothesized that in such patients, severity of OSA is related to …
[HTML][HTML] Trial of an intervention to improve acute heart failure outcomes
Background Patients with acute heart failure are frequently or systematically hospitalized,
often because the risk of adverse events is uncertain and the options for rapid follow-up are …
often because the risk of adverse events is uncertain and the options for rapid follow-up are …
The oxidative stress hypothesis of congestive heart failure: radical thoughts
S Mak, GE Newton - Chest, 2001 - Elsevier
There is extensive experimental evidence from in vitro and animal experiments that
congestive heart failure (CHF) is a state of oxidative stress. Moreover, in animal models, the …
congestive heart failure (CHF) is a state of oxidative stress. Moreover, in animal models, the …
'The Future is Probably Now': Understanding of illness, uncertainty and end‐of‐life discussions in older adults with heart failure and family caregivers
J Im, S Mak, R Upshur, L Steinberg… - Health …, 2019 - Wiley Online Library
Background Earlier end‐of‐life communication is critical for people with heart failure given
the uncertainty and high‐risk of mortality in illness. Despite this, end‐of‐life communication is …
the uncertainty and high‐risk of mortality in illness. Despite this, end‐of‐life communication is …
Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea
…, CM Ryan, GE Newton, S Mak… - Archives of internal …, 2006 - jamanetwork.com
Background Adverse effects of obstructive sleep apnea (OSA), including sleep deprivation,
can contribute to the progression of heart failure. The usual indication to diagnose and treat …
can contribute to the progression of heart failure. The usual indication to diagnose and treat …
Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction
D Yumino, H Wang, JS Floras, GE Newton, S Mak… - Journal of cardiac …, 2009 - Elsevier
BACKGROUND: Previous studies reported high prevalences of obstructive and central
sleep apnea (OSA and CSA, respectively) in patients with heart failure (HF). However, these …
sleep apnea (OSA and CSA, respectively) in patients with heart failure (HF). However, these …
Effect of hyperoxia on left ventricular function and filling pressures in patients with and without congestive heart failure
S Mak, ER Azevedo, PP Liu, GE Newton - Chest, 2001 - Elsevier
… Author links open overlay panel Susanna Mak MD a , Eduardo R. Azevedo MD b , Peter P. …
Mak and Azevedo are Research Fellows of the Heart and Stroke Foundation, Dr. Liu holds …
Mak and Azevedo are Research Fellows of the Heart and Stroke Foundation, Dr. Liu holds …
[HTML][HTML] A high-sodium diet is associated with acute decompensated heart failure in ambulatory heart failure patients: a prospective follow-up study
…, V Floras, A Al-Hesayen, ER Azevedo, S Mak… - The American journal of …, 2011 - Elsevier
Background: A low-sodium diet is an accepted treatment of patients with heart failure (HF),
although minimal evidence exists on the appropriate amount of sodium intake for this …
although minimal evidence exists on the appropriate amount of sodium intake for this …