Influence of obstructive sleep apnea on mortality in patients with heart failure

…, JD Parker, GE Newton, JS Floras, S Mak… - Journal of the American …, 2007 - jacc.org
Objectives : This study sought to determine, in patients with heart failure (HF), whether untreated
moderate to severe obstructive sleep apnea (OSA) is associated with a higher mortality …

Tissue expression and immunolocalization of tumor necrosis factor-α in postinfarction dysfunctional myocardium

MW Irwin, S Mak, DL Mann, R Qu, JM Penninger… - Circulation, 1999 - Am Heart Assoc
Background—Tumor necrosis factor-α (TNF-α) is markedly elevated in advanced heart
failure. It is not known whether tissue TNF-α is elevated in the common setting of myocardial …

Nocturnal rostral fluid shift: a unifying concept for the pathogenesis of obstructive and central sleep apnea in men with heart failure

…, MC Su, S Smith, GE Newton, S Mak… - Circulation, 2010 - Am Heart Assoc
Background— Obstructive sleep apnea (OSA) and central sleep apnea are common in
patients with heart failure. We hypothesized that in such patients, severity of OSA is related to …

[HTML][HTML] Trial of an intervention to improve acute heart failure outcomes

…, J Fang, JA Udell, MJ Schull, S Mak… - … England Journal of …, 2023 - Mass Medical Soc
Background Patients with acute heart failure are frequently or systematically hospitalized,
often because the risk of adverse events is uncertain and the options for rapid follow-up are …

The oxidative stress hypothesis of congestive heart failure: radical thoughts

S Mak, GE Newton - Chest, 2001 - Elsevier
There is extensive experimental evidence from in vitro and animal experiments that
congestive heart failure (CHF) is a state of oxidative stress. Moreover, in animal models, the …

'The Future is Probably Now': Understanding of illness, uncertainty and end‐of‐life discussions in older adults with heart failure and family caregivers

J Im, S Mak, R Upshur, L Steinberg… - Health …, 2019 - Wiley Online Library
Background Earlier end‐of‐life communication is critical for people with heart failure given
the uncertainty and high‐risk of mortality in illness. Despite this, end‐of‐life communication is …

Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea

…, CM Ryan, GE Newton, S Mak… - Archives of internal …, 2006 - jamanetwork.com
Background Adverse effects of obstructive sleep apnea (OSA), including sleep deprivation,
can contribute to the progression of heart failure. The usual indication to diagnose and treat …

Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction

D Yumino, H Wang, JS Floras, GE Newton, S Mak… - Journal of cardiac …, 2009 - Elsevier
BACKGROUND: Previous studies reported high prevalences of obstructive and central
sleep apnea (OSA and CSA, respectively) in patients with heart failure (HF). However, these …

Effect of hyperoxia on left ventricular function and filling pressures in patients with and without congestive heart failure

S Mak, ER Azevedo, PP Liu, GE Newton - Chest, 2001 - Elsevier
… Author links open overlay panel Susanna Mak MD a , Eduardo R. Azevedo MD b , Peter P. …
Mak and Azevedo are Research Fellows of the Heart and Stroke Foundation, Dr. Liu holds …

[HTML][HTML] A high-sodium diet is associated with acute decompensated heart failure in ambulatory heart failure patients: a prospective follow-up study

…, V Floras, A Al-Hesayen, ER Azevedo, S Mak… - The American journal of …, 2011 - Elsevier
Background: A low-sodium diet is an accepted treatment of patients with heart failure (HF),
although minimal evidence exists on the appropriate amount of sodium intake for this …