[HTML][HTML] Protective role for caspase-11 during acute experimental murine colitis

…, M Raverdeau, G Aviello, SC Wade… - The Journal of …, 2015 - journals.aai.org
Activation of the noncanonical inflammasome, mediated by caspase-11, serves as an
additional pathway for the production of the proinflammatory cytokines IL-1β and IL-18. …

Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis

SM Wade, M Canavan, T McGarry, C Low… - Annals of the …, 2019 - ard.bmj.com
Objective This study examines polyfunctional T-cells in psoriatic arthritis (PsA) synovial
tissue and their associations with clinical disease and implications for therapy. Methods PsA …

[HTML][HTML] Monocyte-derived dendritic cell differentiation in inflammatory arthritis is regulated by the JAK/STAT axis via NADPH oxidase regulation

V Marzaioli, M Canavan, A Floudas, SC Wade… - Frontiers in …, 2020 - frontiersin.org
Monocyte-derived Dendritic cells (Mo-DC) are a distinct DC subset, involved in inflammation
and infection, they originate from monocytes upon stimulation in the circulation and their …

Serum MicroRNA signature as a diagnostic and therapeutic marker in patients with psoriatic arthritis

SM Wade, T McGarry, SC Wade, U Fearon… - The Journal of …, 2020 - jrheum.org
Objective MicroRNA (miRNA) are small endogenous regulatory RNA molecules that have
emerged as potential therapeutic targets and biomarkers in autoimmunity. Here, we …

[HTML][HTML] Targeting JAK-STAT signalling alters PsA synovial fibroblast pro-inflammatory and metabolic function

A O'Brien, MM Hanlon, V Marzaioli, SC Wade… - Frontiers in …, 2021 - frontiersin.org
Objectives Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis.
Janus Kinase inhibitors (JAKi) have emerged as an encouraging class of drugs for the …

[HTML][HTML] Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B

SM Wade, M Trenkmann, T McGarry, M Canavan… - Journal of …, 2019 - Elsevier
Objectives To investigate the functional role of miR-23a in synovial fibroblasts (SFC)
activation in psoriatic arthritis (PsA). Methods Differential expression of the miR-23a-27a-24-2 …

Estrogen receptor (ER) α and ERβ exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway

CB Wade, S Robinson, RA Shapiro, DM Dorsa - Endocrinology, 2001 - academic.oup.com
The rapid, nongenomic effects of estrogen are increasingly recognized as playing an
important role in several aspects of estrogen action. Rapid activation of the mitogen-activated …

[CITATION][C] THIS GEORGETOWN LAW OURNAL

MM CALKINS - search.proquest.com
Wade Weems PAROLE Erin W. Sheehy NEW TRIAL David Booth APPEALS Deborah
McCoppin Mikal J. Condon APPELLATE REVIEW OF SENTENCES Michael O’Shaughnessy …

[HTML][HTML] Elective cancer surgery in COVID-19–free surgical pathways during the SARS-CoV-2 pandemic: an international, multicenter, comparative cohort study

…, KJ Roberts, C San Miguel-Méndez… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in
COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free …

[CITATION][C] Tofacitinib Impairs Monocyte-Derived Dendritic Cell Differentiation in Rheumatoid Arthritis and Psoriatic Arthritis.

…, A Floudas, SC Wade, C Low… - ARTHRITIS & …, 2018 - … ST, HOBOKEN 07030-5774, NJ USA