Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with …

…, CP Tena, CR Remus, JCR Rodriguez, SJ Hong… - The Lancet, 2018 - thelancet.com
Background Biological disease-modifying anti-rheumatic drugs (bDMARDs) are recommended
for radiographic axial spondyloarthritis, otherwise known as ankylosing spondylitis, when …

[HTML][HTML] Efficacy and safety of ixekizumab in the treatment of radiographic axial spondyloarthritis: sixteen‐week results from a phase III randomized, double‐blind …

…, M Greenwald, E Gremese, SJ Hong… - Arthritis & …, 2019 - Wiley Online Library
Objective To investigate the efficacy and safety of ixekizumab in patients with active radiographic
axial spondyloarthritis (SpA) and prior inadequate response to or intolerance of 1 or 2 …

Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial

…, CFP Tena, CRR Remus, JCR Rodriguez, SJ Hong… - The Lancet, 2020 - thelancet.com
Background Ixekizumab, a high-affinity interleukin-17A (IL-17A) monoclonal antibody, has
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …

Anti-inflammatory effects of methanol extract of Patrinia scabiosaefolia in mice with ulcerative colitis

E Cho, JS Shin, YS Noh, YW Cho, SJ Hong… - Journal of …, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Patrinia scabiosaefolia Fisch is used in folk
medicines to treat intestinal abscesses, acute appendicitis, and dysentery in Asia. Although …

[HTML][HTML] Progress in oral microbiome related to oral and systemic diseases: an update

YH Lee, SW Chung, QS Auh, SJ Hong, YA Lee, J Jung… - Diagnostics, 2021 - mdpi.com
The human oral microbiome refers to an ecological community of symbiotic and pathogenic
microorganisms found in the oral cavity. The oral cavity is an environment that provides …

Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis

…, HM Choi, YA Lee, IA Choi, SH Lee, SJ Hong… - Rheumatology …, 2011 - Springer
This study was performed to provide evidence, albeit indirectly, as to which matrix
metalloproteinases (MMPs), among the gelatinases MMP-2 and MMP-9 and the collagenases …

[HTML][HTML] Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase …

HM Choi, YA Lee, SH Lee, SJ Hong, DH Hahm… - Arthritis research & …, 2009 - Springer
Introduction The role of adiponectin in the pathogenesis of arthritis is still controversial. This
study was performed to examine whether adiponectin is involved in joint inflammation and …

[HTML][HTML] Determinants of quality of life in patients with fibromyalgia: A structural equation modeling approach

…, SH Kim, SS Nah, JH Lee, SK Kim, YA Lee, SJ Hong… - PloS one, 2017 - journals.plos.org
Objective Health-related quality of life (HRQOL) in patients with fibromyalgia (FM) is lower
than in patients with other chronic diseases and the general population. Although various …

Segmented polyurethanes and thermoplastic elastomers from elemental sulfur with enhanced thermomechanical properties and flame retardancy

…, DA Loy, M Kwon, H Paik, SJ Hong… - Angewandte Chemie …, 2021 - Wiley Online Library
The production of elemental sulfur from petroleum refining has created a technological
opportunity to increase the valorization of elemental sulfur by the creation of high‐performance …

Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis

SJ Hong, GS Rim, HI Yang, CS Yin, HG Koh, MH Jang… - Toxicon, 2005 - Elsevier
Bee venom (BV) has been used traditionally for the control of pain and inflammation in various
chronic inflammatory diseases, including rheumatoid arthritis (RA) in Oriental medicine. …