[HTML][HTML] NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion
S Massone, E Ciarlo, S Vella, M Nizzari, T Florio… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Neuroblastoma Differentiation Marker 29 (NDM29) is a RNA polymerase (pol) III-transcribed
non-coding (nc) RNA whose synthesis drives neuroblastoma (NB) cell differentiation to a …
non-coding (nc) RNA whose synthesis drives neuroblastoma (NB) cell differentiation to a …
Advances in emerging drugs for osteosarcoma
CM Hattinger, M Fanelli, E Tavanti, S Vella… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Osteosarcoma (OS), the most common primary malignant bone tumor, is
currently treated with pre- and postoperative chemotherapy in association with the surgical …
currently treated with pre- and postoperative chemotherapy in association with the surgical …
[HTML][HTML] Comparison of immunosuppressive and angiogenic properties of human amnion-derived mesenchymal stem cells between 2D and 3D culture systems
The secretion of potential therapeutic factors by mesenchymal stem cells (MSCs) has
aroused much interest given the benefits that it can bring in the field of regenerative medicine. …
aroused much interest given the benefits that it can bring in the field of regenerative medicine. …
[HTML][HTML] Selection of candidate housekeeping genes for normalization in human postmortem brain samples
I Penna, S Vella, A Gigoni, C Russo… - International journal of …, 2011 - mdpi.com
The most frequently used technique to study the expression profile of genes involved in
common neurological disorders is quantitative real-time RT-PCR, which allows the indirect …
common neurological disorders is quantitative real-time RT-PCR, which allows the indirect …
Dichloroacetate inhibits neuroblastoma growth by specifically acting against malignant undifferentiated cells
The small, water soluble molecule Dichloroacetate (DCA) is recently arousing lively interests
in the field of cancer therapy for it has been shown to be able to inhibit the growth of human …
in the field of cancer therapy for it has been shown to be able to inhibit the growth of human …
Targeting ABCB1 and ABCC1 with their specific inhibitor CBT-1® can overcome drug resistance in osteosarcoma
M Fanelli, C Maria Hattinger, S Vella… - Current cancer drug …, 2016 - ingentaconnect.com
Clinical treatment response achievable with conventional chemotherapy in high-grade
osteosarcoma (OS) is severely limited by the presence of intrinsic or acquired drug resistance, …
osteosarcoma (OS) is severely limited by the presence of intrinsic or acquired drug resistance, …
[HTML][HTML] Global profiling of viral and cellular non-coding RNAs in Epstein–Barr virus-induced lymphoblastoid cell lines and released exosome cargos
A Gallo, S Vella, M Miele, F Timoneri, M Di Bella… - Cancer letters, 2017 - Elsevier
The human EBV-transformed lymphoblastoid cell line (LCL), obtained by infecting peripheral
blood monocular cells with Epstein–Barr Virus, has been extensively used for human …
blood monocular cells with Epstein–Barr Virus, has been extensively used for human …
[HTML][HTML] PIWI-interacting RNA (piRNA) signatures in human cardiac progenitor cells
S Vella, A Gallo, AL Nigro, D Galvagno… - The international journal …, 2016 - Elsevier
Cardiac progenitors, such as cardiospheres and cardiosphere-derived cells, represent an
attractive cell source for cardiac regeneration. The PIWI-interacting RNAs, piRNAs, are an …
attractive cell source for cardiac regeneration. The PIWI-interacting RNAs, piRNAs, are an …
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids
Among the different species of water-soluble β-peptides (Aβ1-42, Aβ1-40 and N-terminal
truncated Aβ-peptides), Aβpy3-42 is thought to play a relevant role in Alzheimer's pathogenesis …
truncated Aβ-peptides), Aβpy3-42 is thought to play a relevant role in Alzheimer's pathogenesis …
[HTML][HTML] Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA
S Vella, I Penna, L Longo, G Pioggia, P Garbati… - Scientific reports, 2015 - nature.com
High Risk Neuroblastoma (HR-NB) is a pediatric cancer characterized by high malignancy
and remarkable cell heterogeneity within the tumour nodules. In a recent study, we …
and remarkable cell heterogeneity within the tumour nodules. In a recent study, we …