BACKGROUND: Estimation of glomerular filtration rate (GFR) is limited by differences in
creatinine generation among ethnicities. Our previously reported GFR-estimating equations for …

End-stage renal disease (ESRD) is associated with significantly increased morbidity and
mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50% and …

Background We previously estimated the prevalence of chronic kidney disease (CKD) stages
3–5 at 19.1 million based on data from the Japanese annual health check program for …

Background Accurate estimation of the glomerular filtration rate (GFR) is crucial for the
detection of chronic kidney disease (CKD). In clinical practice, GFR is estimated from serum …

Vascular endothelial growth factor (VEGF) plays a critical role during normal embryonic
angiogenesis and also in the pathological angiogenesis that occurs in a number of diseases, …

Background The demographic structure of a country changes dramatically with increasing
trends toward general population aging and declining birth rates. In J apan, the percentage of …

INTRODUCTION: We previously reported a modification to the Modification of Diet in Renal
Disease (MDRD) Study equation for use in Japan. Recently, the Chronic Kidney Disease …

BACKGROUND: Glomerular filtration rate (GFR)-estimating equations based on serum
creatinine level may not be accurate across racial groups because of differences among races in …

The prevalence of stage 3 to 5 chronic kidney disease (CKD) in Japan (18.7%) is considerably
higher than that in the United States (4.5%). This study investigated in the Japanese …

Background The number of patients with end-stage renal disease (ESRD) in Japan has
continuously increased in the past three decades. In 2005, 36 063 patients whose average age …