Aspects of immune dysfunction in end-stage renal disease

S Kato, M Chmielewski, H Honda… - Clinical Journal of the …, 2008 - journals.lww.com
End-stage renal disease (ESRD) is associated with significantly increased morbidity and
mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50% and …

[HTML][HTML] Comparison of nutritional and inflammatory markers in dialysis patients with reduced appetite

…, J Axelsson, CM Avesani, ME Suliman, S Kato… - The American journal of …, 2007 - Elsevier
Background:Anorexia is common in chronic kidney disease and worsens as the disease
progresses. Sex hormones and inflammatory cytokines may be related to feeding behavior. …

Characteris Tics and causes of Immune Dysfunction related to Uremia and Dialysis

AB Hauser, AEM Stinghen, S Kato… - Peritoneal Dialysis …, 2008 - journals.sagepub.com
From the immunologic viewpoint, chronic kidney disease (CKD) is characterized by
disorders of both the innate and adaptive systems, generating a complex and still not fully …

[HTML][HTML] Clinical impact of kidney function on presepsin levels

…, Y Yasuda, M Ando, T Abe, T Katsuno, S Kato… - PloS one, 2015 - journals.plos.org
Objective Presepsin is highlighted as a diagnostic and prognostic marker of sepsis. Little
information is available regarding the accurate association between presepsin levels and the …

[PDF][PDF] Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4

S Kato, Y Yuzawa, N Tsuboi, S Maruyama… - JOURNAL …, 2004 - researchgate.net
Acute peritonitis, in which peritoneal mesothelial cells are directly exposed to bacterial
components, is a major cause of peritoneal dysfunction in continuous ambulatory peritoneal …

[HTML][HTML] A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease

…, M Nangaku, S Maruyama, E Imai, K Shoji, S Kato… - Kidney International, 2014 - Elsevier
Elevated serum-soluble urokinase receptor (suPAR) levels have been described in patients
with focal segmental glomerulosclerosis (FSGS) in several different cohorts. However, it …

Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial

S Kato, S Maruyama, H Makino, J Wada… - Clinical and …, 2015 - Springer
Background Several studies have demonstrated that spironolactone has an anti-albuminuric
property in diabetic nephropathy. As an adverse event, spironolactone often induces the …

[HTML][HTML] Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70

…, W Sato, Y Morita, F Sato, Y Miki, S Kato… - Kidney international, 2005 - Elsevier
Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70.
Background Heat shock proteins (HSPs) are well known as cytoprotective proteins. …

Renoprotective effects of topiroxostat for hyperuricaemic patients with overt diabetic nephropathy study (ETUDE study): a prospective, randomized, multicentre clinical …

T Mizukoshi, S Kato, M Ando, H Sobajima… - …, 2018 - Wiley Online Library
Aim We aimed to evaluate the anti‐albuminuric effects of topiroxostat in Japanese hyperuricaemic
patients with diabetic nephropathy. Methods In this 24‐week, multicentre, open‐label, …

Impact of abdominal aortic calcification on long-term cardiovascular outcomes in patients with chronic kidney disease

…, K Shibata, M Niwa, R Morimoto, M Hayashi, S Kato… - Atherosclerosis, 2015 - Elsevier
Background The presence of abdominal aortic calcification (AAC) can predict cardiovascular
(CV) outcomes in hemodialysis patients. However, little is known about the predictive value …