Around-the-clock, controlled-release oxycodone therapy for osteoarthritis-related pain: placebo-controlled trial and long-term evaluation

SH Roth, RM Fleischmann, FX Burch… - Archives of Internal …, 2000 - jamanetwork.com
Background Although opioid analgesics have well-defined efficacy and safety in treatment
of chronic cancer pain, further research is needed to define their role in treatment of chronic …

[HTML][HTML] Efficacy and safety of a once-daily morphine formulation in chronic, moderate-to-severe osteoarthritis pain: results from a randomized, placebo-controlled …

…, JC Davis, HL Offenberg, HW Marker, SH Roth… - Journal of pain and …, 2002 - Elsevier
A randomized, 4-week, double-blind trial followed by an open-label extension trial assessed
the efficacy and safety of a once-daily, extended-release morphine formulation (Avinza™ (…

Efficacy and safety of a topical diclofenac solution (pennsaid) in the treatment of primary osteoarthritis of the knee: a randomized, double-blind, vehicle-controlled …

SH Roth, JZ Shainhouse - Archives of internal medicine, 2004 - jamanetwork.com
Background Oral nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to
relieve the symptoms of osteoarthritis (OA) but can produce harmful systemic effects and end-…

[HTML][HTML] Efficacy and safety of extended-release, once-daily tramadol in chronic pain: a randomized 12-week clinical trial in osteoarthritis of the knee

N Babul, R Noveck, H Chipman, SH Roth… - Journal of pain and …, 2004 - Elsevier
The efficacy and safety of a once-daily extended-release formulation of tramadol
hydrochloride (tramadol ER) was evaluated in patients with moderate to severe chronic pain of …

Coming to terms with nonsteroidal anti-inflammatory drug gastropathy

SH Roth - Drugs, 2012 - Springer
Despite well known complications, oral nonsteroidal anti-inflammatory drugs (NSAIDs) remain
the most commonly prescribed medications in the US for musculoskeletal disorders such …

Nonsteroidal anti-inflammatory drug gastropathy: recognition and response

SH Roth, RE Bennett - Archives of Internal Medicine, 1987 - jamanetwork.com
• Gastropathy, recognized as gastric lesional disease ranging from erosions to actual ulcer
craters, represents the most ubiquitous significant complication of common nonsteroidal anti-…

Efficacy and safety of tramadol HCl in breakthrough musculoskeletal pain attributed to osteoarthritis.

SH Roth - The Journal of rheumatology, 1998 - europepmc.org
Objective To evaluate the efficacy of tramadol as adjunctive therapy in patients with
musculoskeletal pain attributed to osteoarthritis (OA) who experienced breakthrough pain while …

From experiment to experience: side effects of nonsteroidal anti-inflammatory drugs

LS Coles, JF Fries, RG Kraines, SH Roth - The American journal of …, 1983 - Elsevier
As part of the approval process, new drugs are first studied in controlled clinical trials with
carefully selected patients. After gaining approval, however, these drugs are often used in the …

The Prosorba column for treatment of refractory rheumatoid arthritis: a randomized, double‐blind, sham‐controlled trial

…, ER Harris, EL Matteson, SH Roth… - … : Official Journal of …, 1999 - Wiley Online Library
Objective To evaluate the efficacy and safety of the Prosorba column as a treatment for
rheumatoid arthritis (RA) in patients with active and treatment‐resistant (refractory) disease. …

A multicenter study of annual health service utilization and costs in rheumatoid arthritis

…, JF Fries, F Wolfe, DM Mitchell, SH Roth - … : Official Journal of …, 1986 - Wiley Online Library
The economic impact of chronic illness has important implications for medical practice and
health policy. To determine the yearly costs of illness for those who have rheumatoid arthritis, …