The synovium is the major target tissue of inflammatory arthritides such as rheumatoid arthritis.
The study of synovial tissue has advanced considerably throughout the past few decades …

T helper 17 (Th17) cells are important mediators of immune responses against extracellular
bacteria and fungi, and as such play critical regulatory roles in maintaining mucosal …

Angiogenesis is de novo capillary outgrowth from pre-existing blood vessels. This process
not only is crucial for normal development, but also has an important role in supplying oxygen …

Background Data are scarce on immunogenicity of COVID-19 vaccines in patients with
autoimmune diseases, who are often treated with immunosuppressive drugs. We aimed to …

Mannan-binding lectin (MBL), a member of the collectin family, is known to have opsonic
function, although identification of its cellular receptor has been elusive. Complement C1q, …

Background Disease-specific studies have reported impaired humoral responses after
SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders treated with …

Here we report the transcriptional profile of human microglia, isolated from normal-appearing
grey matter (GM) and white matter (WM) of multiple sclerosis (MS) and non-neurological …

Objectives We explored the effects of B-cell directed therapy in subjects at risk of developing
autoantibodypositive rheumatoid arthritis (RA), who never experienced inflammatory …

Dendritic cells (DCs) have been proposed to play a pivotal role in the initiation and
perpetuation of rheumatoid arthritis (RA) by presentation of arthritogenic antigens to T cells. We …

June 18, 2021 https://doi. org/10.1016/S2665-9913 (21) 00181-8 digital platforms has had
an adverse impact on diversity and participation from under-represented groups due to …