OBJECTIVE—To examine the effect of aging on insulin secretion (first- and second-phase
insulin release) and insulin sensitivity in people with normal glucose tolerance (NGT) or …

Background Motor fluctuations and dyskinesias can cause disability and reduce quality of
life for patients with Parkinson disease (PD). Objectives To evaluate factors associated with …

OBJECTIVE: To compare the efficacy of gabapentin, estrogen, and placebo in the treatment
of hot flushes. METHODS: We performed a randomized, double-blind, placebo-controlled …

Introduction Clinical trials of new treatments for rheumatoid arthritis (RA) typically require
subjects to have an elevated acute phase reactant (APR), in addition to tender and swollen …

BACKGROUND: The scientific method requires that only experiments actually and correctly
performed be used to draw conclusions. The intention‐to‐treat principle requires that all …

Background Vitamin D deficiency is a re-emerging epidemic, especially in minority
populations. Vitamin D is crucial not only for bone health but for proper brain development and …

By analysis of the American College of Surgeons National Surgical Quality Improvement
Program database, we identified factors associated with postoperative complications and …

Objective Prior studies on the association of trait neuroticism and cognitive function in older
adults have yielded mixed findings. The authors tested hypotheses that neuroticism is …

Background: Batten disease (juvenile neuronal ceroid lipofuscinosis [JNCL]) is an autosomal
recessive neurodegenerative disorder characterized by blindness, seizures, and relentless …

Objective: To establish the relationship between operative approach (laparoscopic or open)
and subsequent surgical infection (both incisional and organ space infection) …