[HTML][HTML] Hepatic expression patterns of inflammatory and immune response genes associated with obesity and NASH in morbidly obese patients

A Bertola, S Bonnafous, R Anty, S Patouraux… - PloS one, 2010 - journals.plos.org
Background Obesity modulates inflammation and activation of immune pathways which can
lead to liver complications. We aimed at identifying expression patterns of inflammatory and …

A new composite model including metabolic syndrome, alanine aminotransferase and cytokeratin‐18 for the diagnosis of non‐alcoholic steatohepatitis in morbidly …

R Anty, A Iannelli, S Patouraux… - Alimentary …, 2010 - Wiley Online Library
Aliment Pharmacol Ther 2010; 32: 1315–1322 Summary Background Non‐invasive approaches
are useful to differentiate simple steatosis from non‐alcoholic steatohepatitis (NASH) in …

Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing …

R Anty, S Marjoux, A Iannelli, S Patouraux… - Journal of …, 2012 - Elsevier
BACKGROUND & AIMS: The aim of this study was to determine the influence of coffee and
other caffeinated drinks on liver fibrosis of severely obese European patients. METHODS: A …

CD44 is a key player in non-alcoholic steatohepatitis

S Patouraux, D Rousseau, S Bonnafous… - Journal of …, 2017 - Elsevier
… Author links open overlay panel Stéphanie Patouraux 1 2 3 † , Déborah Rousseau 1 2 † ,
Stéphanie Bonnafous 1 2 4 , Cynthia Lebeaupin 1 2 , Carmelo Luci 1 2 , Clémence M. Canivet …

[HTML][HTML] Endoplasmic reticulum-mitochondria miscommunication is an early and causal trigger of hepatic insulin resistance and steatosis

…, A Vieille-Marchiset, CC Da Silva, S Patouraux… - Journal of …, 2022 - Elsevier
Background & Aims Hepatic insulin resistance in obesity and type 2 diabetes was recently
associated with endoplasmic reticulum (ER)-mitochondria miscommunication. These contact …

Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice

…, X Mouska, S Bonnafous, S Patouraux… - Science translational …, 2013 - science.org
Achondroplasia is a rare genetic disease characterized by abnormal bone development,
resulting in short stature. It is caused by a single point mutation in the gene coding for fibroblast …

[PDF][PDF] Bax inhibitor‐1 protects from nonalcoholic steatohepatitis by limiting inositol‐requiring enzyme 1 alpha signaling in mice

C Lebeaupin, D Vallée, D Rousseau, S Patouraux… - …, 2018 - Wiley Online Library
Endoplasmic reticulum (ER) stress is activated in nonalcoholic fatty liver disease (NAFLD),
raising the possibility that ER stress‐dependent metabolic dysfunction, inflammation, and cell …

[HTML][HTML] The osteopontin level in liver, adipose tissue and serum is correlated with fibrosis in patients with alcoholic liver disease

S Patouraux, S Bonnafous, CS Voican, R Anty… - PloS one, 2012 - journals.plos.org
Background Osteopontin (OPN) plays an important role in the progression of chronic liver
diseases. We aimed to quantify the liver, adipose tissue and serum levels of OPN in heavy …

[HTML][HTML] Study of LAT1 expression in brain metastases: towards a better understanding of the results of positron emission tomography using amino acid tracers

…, M Dufour, F Almairac, M Coutts, S Patouraux… - PloS one, 2016 - journals.plos.org
Positron emission tomography using radiolabeled amino acid (PET-AA) appears to be
promising in distinguishing between recurrent tumour and radionecrosis in the follow-up of brain …

Screening for therapeutic trials and treatment indication in clinical practice: MACK‐3, a new blood test for the diagnosis of fibrotic NASH

…, A Iannelli, L Van Gaal, S Patouraux… - Alimentary …, 2018 - Wiley Online Library
Background The composite histological endpoint comprising nonalcoholic steatohepatitis (
NASH ) and NAFLD activity score ≥4 and advanced fibrosis (F ≥ 2) (“fibrotic NASH ”) is …