A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by …

…, AK Ulfgren, S RantapääDahlqvist… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To investigate whether smoking and HLA–DR shared epitope (SE) genes may
interact in triggering immune reactions to citrulline‐modified proteins. Methods In a case–…

Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis

S RantapääDahlqvist, BAW De Jong… - Arthritis & …, 2003 - Wiley Online Library
Objective To evaluate the prevalence and predictive value of anti–cyclic citrullinated peptide
(anti‐CCP) antibodies in individuals who subsequently developed rheumatoid arthritis (RA) …

Genetics of rheumatoid arthritis contributes to biology and drug discovery

…, L Rodriguez-Rodriguez, S Rantapää-Dahlqvist… - Nature, 2014 - nature.com
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

[HTML][HTML] Association of Systemic Lupus Erythematosus with C8orf13–BLK and ITGAM–ITGAX

…, AA Bengtsson, S Rantapää-Dahlqvist… - … England Journal of …, 2008 - Mass Medical Soc
Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in
which the risk of disease is influenced by complex genetic and environmental contributions. …

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

…, A Jönsen, AA Bengtsson, S Rantapää-Dahlqvist… - Nature …, 2009 - nature.com
Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

…, L Ärlsetig, J Martin, S Rantapää-Dahlqvist… - Nature …, 2012 - nature.com
Using the Immunochip custom SNP array, which was designed for dense genotyping of 186
loci identified through genome-wide association studies (GWAS), we analyzed 11,475 …

[PDF][PDF] Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

…, G Sturfelt, A Jönsen, S Rantapää-Dahlqvist… - The American Journal of …, 2005 - cell.com
Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease caused by
both genetic and environmental factors. Genome scans in families with SLE point to multiple …

Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden

…, J Lysholm, S RantapääDahlqvist… - Arthritis & …, 2005 - Wiley Online Library
Objective Because treatment with tumor necrosis factor (TNF) antagonists may increase the
risk of tuberculosis (TB), and because knowledge of the risk of TB in rheumatoid arthritis (RA…

Up‐regulation of cytokines and chemokines predates the onset of rheumatoid arthritis

…, K Lejon, S Rantapää Dahlqvist - … : Official Journal of …, 2010 - Wiley Online Library
Solbritt Rantapää DahlqvistRantapää Dahlqvist had full access to all of the data in the
study and takes responsibility for the integrity of the data and the accuracy of the data analysis. …

Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis. A retrospective cohort study from disease onset.

…, ML Ohman, S Rantapää-Dahlqvist - The Journal of …, 1999 - europepmc.org
Objective To identify predictors for cardiovascular disease (CVD) and for overall survival in
patients with rheumatoid arthritis (RA) followed from disease onset. Methods A retrospective …