Background Pompe's disease is a metabolic myopathy caused by a deficiency of acid alpha
glucosidase (GAA), an enzyme that degrades lysosomal glycogen. Late-onset Pompe's …

We describe a long-term observational study of a large cohort of patients with sporadic
inclusion body myositis and propose a sporadic inclusion body myositis weakness composite …

Necrotizing autoimmune myopathy (NAM) is a group of acquired myopathies characterized
by prominent myofiber necrosis with little or no muscle inflammation. Recently, researchers …

purpose: Polymyositis and dermatomyositis are inflammatory muscular diseases of unknown
cause. Many interventions are available to treat patients with these conditions including …

Objective Anti–signal recognition particle (anti‐SRP) autoantibodies are associated with
severe acquired necrotizing myopathies. The role of these autoantibodies remains elusive, and …

Objective To assess prevalence and characteristics of opportunistic infections in patients
with polymyositis/dermatomyositis (PM/DM). To determine the predictive values for …

Nine patients with Duchenne or Becker muscular dystrophy were injected via the radialis
muscle with a full-length human dystrophin plasmid, either once with 200 or 600 µg of DNA or …

Objective Anti-synthetase syndrome (anti-SS) is frequently associated with myositis and
interstitial lung disease (ILD). We evaluated prospectively, in a multicenter, open-label, phase II …

OBJECTIVE: To develop diagnostic imaging criteria for polymyositis (PM) and sporadic
inclusion body myositis (sIBM). METHODS: We investigated 220 patients with suspected …

Objective To describe the clinical, biologic, and histologic features of temporal artery biopsy
(TAB)–localized systemic necrotizing vasculitides (SNV), and to assess their frequency …