Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis …
CP Cannon, SP Curtis, GA FitzGerald, H Krum, A Kaur… - The Lancet, 2006 - thelancet.com
Background Cyclo-oxygenase-2 (COX-2) selective inhibitors have been associated with an
increased risk of thrombotic cardiovascular events in placebo-controlled trials, but no clinical …
increased risk of thrombotic cardiovascular events in placebo-controlled trials, but no clinical …
[HTML][HTML] Lung eQTLs to help reveal the molecular underpinnings of asthma
…, C Zhang, R Vessey, GJ Opiteck, SP Curtis… - PLoS …, 2012 - journals.plos.org
Genome-wide association studies (GWAS) have identified loci reproducibly associated with
pulmonary diseases; however, the molecular mechanism underlying these associations are …
pulmonary diseases; however, the molecular mechanism underlying these associations are …
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and …
L Laine, SP Curtis, B Cryer, A Kaur, CP Cannon - The Lancet, 2007 - thelancet.com
Background Upper gastrointestinal safety of cyclo-oxygenase (COX)-2 selective inhibitors
versus traditional non-steroidal anti-inflammatory drugs (NSAIDs) has not been assessed in …
versus traditional non-steroidal anti-inflammatory drugs (NSAIDs) has not been assessed in …
[PDF][PDF] Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale
meta-analyses by using a custom ∼50,000 SNP genotyping array (the ITMAT-Broad-CARe …
meta-analyses by using a custom ∼50,000 SNP genotyping array (the ITMAT-Broad-CARe …
[PDF][PDF] Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis
Elevated body mass index (BMI) associates with cardiometabolic traits on observational
analysis, yet the underlying causal relationships remain unclear. We conducted Mendelian …
analysis, yet the underlying causal relationships remain unclear. We conducted Mendelian …
Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and …
MT Burniston, A Cimarelli, J Colgan, SP Curtis… - Journal of …, 1999 - Am Soc Microbiol
The human immunodeficiency virus type 1 (HIV-1) Gag polyprotein directs the formation of
virions from productively infected cells. Manygag mutations disrupt virion assembly, but little is …
virions from productively infected cells. Manygag mutations disrupt virion assembly, but little is …
[PDF][PDF] Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci
…, JM Connell, KJ Cruickshanks, SP Curtis… - The American Journal of …, 2014 - cell.com
Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), …
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), …
Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug …
L Laine, SP Curtis, M Langman, DM Jensen, B Cryer… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: Nonsteroidal anti-inflammatory drugs (NSAIDs) cause lower
gastrointestinal (GI) clinical events such as bleeding. Cyclo-oxygenase (COX)-2 selective …
gastrointestinal (GI) clinical events such as bleeding. Cyclo-oxygenase (COX)-2 selective …
Loci influencing blood pressure identified using a cardiovascular gene-centric array
…, W Chen, RM Cooper-DeHoff, SP Curtis… - Human molecular …, 2013 - academic.oup.com
Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To
investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial …
investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial …
[HTML][HTML] A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273]
E Collantes, SP Curtis, KW Lee, N Casas… - BMC Family …, 2002 - Springer
… Sean P Curtis … Compared with patients receiving placebo, patients receiving etoricoxib and
naproxen showed significant improvements in all efficacy endpoints (p<0.05). … Sean P Curtis …
naproxen showed significant improvements in all efficacy endpoints (p<0.05). … Sean P Curtis …