Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly evolving …

Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …

Using principal component (PC) analysis, we studied the genetic constitution of 3,112
individuals from Europe as portrayed by more than 270,000 single nucleotide polymorphisms (…

Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …

Objectives To investigate the incidence of COVID-19 in a cohort of adult and paediatric patients
with rheumatic diseases receiving targeted biologic and synthetic disease modifying anti-…

Objectives To evaluate the safety and tolerability of the intravenous administration of Cx611,
a preparation of allogeneic expanded adipose-derived stem cells (eASCs), in patients with …

Background Polygenic scores (PGSs), which assess the genetic risk of individuals for a disease,
are calculated as a weighted count of risk alleles identified in genome-wide association …

Objective Neovascularization, with an increased number of synovial vessels with a
characteristic morphology, seems to contribute to the progression of psoriatic arthritis (PsA). …