OBJECTIVETo characterize trends in outpatient antibiotic prescriptions in the United
StatesDESIGNRetrospective ecological and temporal trend study evaluating outpatient antibiotic …

Objective National estimates of arthritis prevalence rely on a single survey question about
doctor‐diagnosed arthritis without using survey information on joint symptoms, even though …

Importance Patients with septic shock may benefit from the initiation of corticosteroids.
However, the comparative effectiveness of the 2 most studied corticosteroid regimens (…

Background Antibiotic prescribing practices among general dentists and dental specialists
in the United States remains poorly understood. The purpose of this study was to compare …

Objectives Although treatment development in osteoarthritis (OA) focuses on chondroprotection,
it is unclear how much preventing cartilage loss reduces joint pain. It is also unclear …

An explosion of new data sources has increased focus on the use of “real-world” information
to inform patient-centered care. Enthusiasm for such a “learning health care system” is …

OBJECTIVETo evaluate a central line care maintenance bundle to reduce central line–associated
bloodstream infection (CLABSI) in non–intensive care unit settings.DESIGNBefore-…

Objective To examine the association of body mass index (BMI) with pain in people with hand
osteoarthritis (OA), and explore whether this association, if causal, is mediated by systemic …

Background. The long-term and cumulative effect of multiple episodes of bacteremia and
sepsis across multiple hospitalizations on the development of cardiovascular (CV) events is …

Background Urinalysis and urine culture are commonly ordered tests in the emergency
department (ED). We evaluated the impact of removal of order sets from the ‘frequently ordered …