La artritis reumatoide (AR) es una enfermedad autoinmunitaria sistémica caracterizada por
sinovitis y destrucción progresiva del cartílago articular y hueso subyacente, junto con …

IVIg is an approved therapy for immunodeficiency and for several autoimmune and inflammatory
diseases. However, the molecular basis for the IVIg anti-inflammatory activity remains to …

Background There is uncertainty about the impact of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI), a …

… En primer lugar, se seleccionaron las variables que individualmente mostraron las
diferencias estadísticamente más significativas entre los grupos de supervivientes (S) y no …

Monocytes are versatile cells that can express different functional programs in response to
microenvironmental signals. We show that primary blood monocytes secrete the CXCL12 …

Objective Patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular
disease that may not always be related to the presence of traditional cardiovascular risk factors…

… Tejera-Alhambra M, Palomares O, Perez de Diego R, Diaz-Lezcano I, Sanchez-Ramon S.
New biological insights in the immunomodulatory effects of mucosal polybacterial vaccines in …

Common variable immunodeficiency (CVID) is a heterogeneous syndrome characterized by
impaired antibody responses, recurrent infections, inflammatory, autoimmune and …

Heterotrimers composed of B cell CLL/lymphoma 10 (BCL10), mucosa-associated lymphoid
tissue lymphoma translocation protein 1 (MALT1), and caspase recruitment domain–…

Interferon beta-1a (IFNâ-1a) has demonstrated efficacy in multiple sclerosis (MS), although
its mechanism of action remains only partly understood. We evaluated the ex vivo and in vitro …