This study describes a new approach to the determination of all known mannan-binding
lectin (MBL) mutations. The distribution of known variants of the MBL gene in a population of …

Essential effector functions of innate immunity are mediated by complement activation initiated
by soluble pattern recognition molecules: mannan-binding lectin (MBL) and the ficolins. …

A considerable proportion of recurrent miscarriage (RM) cases are caused by recurrent
chromosomally abnormal conceptions. However, in younger patients and patients with multiple …

Complement activation and inflammation have been suggested in the pathogenesis of
diabetic vascular lesions. We investigated serum mannose‐binding lectin (MBL) levels and …

BACKGROUND: A combination of antenatal and postnatal RhD prophylaxis is more effective
in reducing D immunization in pregnancy than postnatal RhD prophylaxis alone. Based on …

A fourth human UDP-GalNAc:polypeptideN-acetylgalactosaminyltransferase, designated
GalNAc-T4, was cloned and expressed. The genomic organization of GalNAc-T4 is distinct …

Activation of the innate immune system plays a major role in nonalcoholic fatty liver disease
(NAFLD). The complement system is an important component of innate immunity that …

A P1 phage clone containing the near complete protein coding region of the human histo-blood
group ABO gene locus was isolated and characterized. The insert was estimated at ≍ 41 …

Inflammation and complement activation via the mannose-binding lectin (MBL) pathway have
been suggested to play a role in the pathogenesis of diabetic microvascular complications. …

Objectives: In previous studies, around half of all hypothyroid patients preferred levo-thyroxine
(L-T4)+ levo-triiodothyronine (L-T3) combination therapy, 25% preferred T4, and 25% had …